LOC100041343 Inhibitors

LOC100041343 Inhibitors like Wortmannin and PIK-75 target PI3K, while Triciribine blocks Akt, collectively suppressing the PI3K/Akt/mTOR pathway crucial for cell growth and survival. If LOC100041343 is regulated by this pathway, these inhibitors could diminish its activity. MEK inhibitors such as SL327 and PD0325901 reduce ERK pathway signaling, which determines cell fate, potentially decreasing LOC100041343 activity if linked to ERK.

Kinase-targeting compounds, LY333531 and Roscovitine, inhibit PKC and CDKs respectively, affecting proteins involved in these pathways which could influence LOC100041343 if it's a substrate. IC261, a CK1 inhibitor, and SP600125, a JNK inhibitor, could modify the activity of proteins in cell cycle and stress response pathways, impacting LOC100041343 if it's associated with CK1 or JNK. SB216763 and SB431542 block GSK-3β and TGF-β receptor kinase, possibly affecting Wnt and TGF-β pathways, and by extension, LOC100041343 activity if it operates within these.