KOR-3 Inhibitors
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
JTC 801 | 244218-51-7 | sc-203614 sc-203614A | 10 mg 50 mg | $128.00 $571.00 | ||
JTC 801 acts as a KOR-3 ligand, distinguished by its capacity to engage in π-π stacking interactions with aromatic residues in receptor binding sites. This compound exhibits a unique electronic configuration that enhances its reactivity, allowing for rapid formation of covalent bonds with nucleophilic sites. Its hydrophobic regions contribute to membrane permeability, while the presence of halogen substituents modulates its electrophilicity, influencing reaction rates and pathways. | ||||||
(±)-J 113397 | 217461-40-0 | sc-204020 sc-204020A | 10 mg 50 mg | $249.00 $1060.00 | ||
(±)-J 113397 functions as a KOR-3 ligand, characterized by its ability to form hydrogen bonds with key amino acid residues, enhancing receptor affinity. Its unique steric profile facilitates selective interactions within the binding pocket, promoting distinct conformational changes in the receptor. The compound's lipophilic characteristics improve its solubility in nonpolar environments, while its halogen groups fine-tune its reactivity, impacting kinetic behavior in various chemical contexts. | ||||||
nor-Binaltorphimine dihydrochloride | 105618-26-6 | sc-396970A sc-396970 | 1 mg 10 mg | $48.00 $186.00 | 4 | |
Acts as a potent and selective antagonist of KOR-3, binding competitively to the receptor, thus inhibiting its activity. | ||||||
BAN ORL 24 | 475150-69-7 | sc-291924 sc-291924A | 10 mg 50 mg | $185.00 $793.00 | ||
BAN ORL 24 acts as a KOR-3 ligand, exhibiting a unique ability to engage in π-π stacking interactions with aromatic residues, which stabilizes its binding to the receptor. Its distinct electronic configuration allows for enhanced dipole-dipole interactions, influencing the overall binding dynamics. Additionally, the compound's hydrophobic regions contribute to its partitioning behavior, affecting its distribution in lipid-rich environments and altering reaction kinetics in specific pathways. | ||||||
Carbetapentane | 77-23-6 | sc-201100 sc-201100A | 100 mg 500 mg | $300.00 $400.00 | 1 | |
Carbetapentane functions as a KOR-3 ligand, characterized by its capacity to form hydrogen bonds with polar amino acids, enhancing receptor affinity. Its unique steric configuration facilitates conformational changes in the receptor, promoting distinct signaling pathways. The compound's hydrophobic characteristics influence its solubility and interaction with membrane structures, potentially altering the kinetics of receptor activation and downstream effects in cellular environments. | ||||||
Carbetapentane citrate | 23142-01-0 | sc-203538 | 100 mg | $114.00 | ||
Carbetapentane citrate acts as a KOR-3 ligand, exhibiting a unique ability to engage in π-π stacking interactions with aromatic residues, which stabilizes receptor conformation. Its specific spatial arrangement allows for selective binding, influencing the receptor's allosteric modulation. The compound's amphiphilic nature enhances its interaction with lipid bilayers, potentially affecting membrane fluidity and altering the dynamics of receptor-ligand interactions in various cellular contexts. | ||||||
SB 612111 hydrochloride | 371980-98-2 (free base) | sc-361347 sc-361347A | 5 mg 25 mg | $128.00 $510.00 | ||
SB 612111 hydrochloride functions as a KOR-3 ligand, characterized by its ability to form hydrogen bonds with key amino acid residues, which facilitates receptor activation. Its unique steric configuration promotes a distinct conformational change in the receptor, enhancing signal transduction pathways. Additionally, the compound's hydrophilic and lipophilic balance may influence its solubility and distribution in biological systems, impacting its interaction kinetics with target proteins. | ||||||
5′-Guanidinonaltrindole di(trifluoroacetate) | 219655-57-9 | sc-252280 | 5 mg | $388.00 | ||
Known for its high affinity and selectivity towards KOR-3, it acts as an antagonist. | ||||||
BRL 52537 hydrochloride | 130497-33-5 | sc-202508 sc-202508A | 10 mg 50 mg | $204.00 $325.00 | ||
Acts as an antagonist, selectively binding to KOR-3 and inhibiting its activation. | ||||||
Compound 101 | 865608-11-3 | sc-507528 | 5 mg | $106.00 | ||
A selective and potent inhibitor of KOR-3, functioning as an antagonist. | ||||||