Date published: 2025-10-25

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KLF6 Inhibitors

KLF6 inhibitors comprise a distinct chemical class tailored to modulate the Krüppel-like factor 6 (KLF6) protein's activity. KLF6, also referred to as Zf9 or BCD1, serves as a zinc finger transcription factor encoded by the KLF6 gene. Its pivotal role involves acting as a transcriptional regulator by binding to specific DNA sequences and exerting control over the expression of target genes. Depending on the cellular context, KLF6 may function as a tumor suppressor, curtailing uncontrolled cell growth, or conversely, promote cell proliferation and enhance survival mechanisms. KLF6 inhibitors are meticulously engineered to interact with the KLF6 protein in a highly selective manner. This precise manipulation allows researchers to delve into KLF6's multifaceted involvement in various cellular processes. By using KLF6 inhibitors in laboratory experiments, scientists gain invaluable insights into the protein's implications in diverse diseases. It's important to emphasize that KLF6 inhibitors primarily serve as indispensable tools for research and discovery. Their significance lies in unraveling the intricate web of molecular mechanisms orchestrated by KLF6, paving the way for a deeper understanding of its role in health and disease.

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Fisetin

528-48-3sc-276440
sc-276440A
sc-276440B
sc-276440C
sc-276440D
50 mg
100 mg
500 mg
1 g
100 g
$51.00
$77.00
$102.00
$153.00
$2856.00
7
(1)

Fisetin inhibits KLF6 by interfering with its DNA binding, disrupting its transcriptional activity, and reducing its expression, thereby suppressing KLF6-dependent gene regulation.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Quercetin inhibits KLF6 through its ability to disrupt protein-protein interactions necessary for KLF6's transcriptional activity and downregulating KLF6-regulated genes.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin inhibits KLF6 by reducing its expression and interfering with its DNA binding, ultimately suppressing KLF6-mediated gene transcription.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol inhibits KLF6 through the modulation of upstream signaling pathways, leading to decreased KLF6 expression and its transcriptional activity.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

Sulforaphane inhibits KLF6 by promoting its degradation and reducing its binding to target gene promoters, thereby suppressing KLF6-dependent gene expression.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$42.00
$72.00
$124.00
$238.00
$520.00
$1234.00
11
(1)

EGCG inhibits KLF6 by interfering with its DNA binding and reducing its transcriptional activity, leading to the downregulation of KLF6-dependent gene expression.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Genistein inhibits KLF6 by disrupting its protein-protein interactions and downregulating KLF6-regulated gene expression, thereby suppressing its activity.

Caffeic Acid

331-39-5sc-200499
sc-200499A
1 g
5 g
$31.00
$61.00
1
(2)

Caffeic Acid inhibits KLF6 by interfering with its DNA binding and reducing its transcriptional activity, leading to the downregulation of KLF6-dependent genes.

Baicalein

491-67-8sc-200494
sc-200494A
sc-200494B
sc-200494C
10 mg
100 mg
500 mg
1 g
$31.00
$41.00
$159.00
$286.00
12
(1)

Baicalein inhibits KLF6 through its ability to disrupt protein-protein interactions necessary for KLF6's transcriptional activity and downregulating KLF6-regulated genes.

Indirubin

479-41-4sc-201531
sc-201531A
5 mg
25 mg
$112.00
$515.00
4
(1)

Indirubin inhibits KLF6 by interfering with its DNA binding and reducing its transcriptional activity, ultimately suppressing KLF6-dependent gene regulation.