Testicular Receptor 2 (TR2, also known as NR2C1) is a nuclear receptor that can act as a transcription factor. There are no known direct chemical activators for TR2. However, several compounds may influence the function of TR2 indirectly through related pathways or cellular processes. TR2 Activators represent a class of chemicals that can influence the function of TR2. These compounds can indirectly influence the function of TR2 through their effects on related cellular pathways.
Chemicals such as 9-cis Retinoic Acid, All-trans Retinoic Acid, Dexamethasone, Estradiol, Progesterone, Testosterone, Diethylstilbestrol, Tamoxifen, T3, T4, Calcitriol, and Pioglitazone can potentially influence TR2 function through their effects on TR2-related pathways. The effects of these chemicals on TR2 function are context-dependent and may vary based on the cellular environment and other biochemical parameters.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
9-cis-Retinoic acid | 5300-03-8 | sc-205589 sc-205589B sc-205589C sc-205589D sc-205589A | 1 mg 25 mg 250 mg 500 mg 5 mg | $71.00 $424.00 $3121.00 $5722.00 $148.00 | 10 | |
9-cis Retinoic Acid, a potent Retinoic Acid Receptor (RAR) agonist, may influence TR2 function through the retinoid signaling pathway. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
All-trans Retinoic Acid, another potent RAR agonist, may influence TR2 function through the retinoid signaling pathway. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $69.00 $266.00 | 8 | |
Mycophenolic acid inhibits inosine monophosphate dehydrogenase, potentially influencing KIR3DL3 through purine metabolism. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $63.00 $182.00 | 8 | |
Estradiol, an estrogen receptor agonist, may influence TR2 function through the estrogen signaling pathway. | ||||||
Progesterone | 57-83-0 | sc-296138A sc-296138 sc-296138B | 1 g 5 g 50 g | $20.00 $52.00 $298.00 | 3 | |
Progesterone, a progesterone receptor agonist, may influence TR2 function through the progesterone signaling pathway. | ||||||
Methotrexate | 59-05-2 | sc-3507 sc-3507A | 100 mg 500 mg | $94.00 $213.00 | 33 | |
Methotrexate inhibits dihydrofolate reductase, affecting purine metabolism and possibly impacting KIR3DL3 expression. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $78.00 $260.00 | 18 | |
Hydroxyurea inhibits ribonucleotide reductase, affecting DNA synthesis and potentially influencing KIR3DL3 expression. | ||||||
Diethylstilbestrol | 56-53-1 | sc-204720 sc-204720A sc-204720B sc-204720C sc-204720D | 1 g 5 g 25 g 50 g 100 g | $71.00 $287.00 $547.00 $1098.00 $2185.00 | 3 | |
Diethylstilbestrol, another potent estrogen receptor agonist, may influence TR2 function through the estrogen signaling pathway. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $272.00 | 18 | |
Tamoxifen, a selective estrogen receptor modulator, may influence TR2 function through the estrogen signaling pathway. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
5-Fluorouracil inhibits thymidylate synthase, affecting DNA synthesis and potentially modulating KIR3DL3 expression. | ||||||