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Diethylstilbestrol (CAS 56-53-1)

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Alternate Names:
4,4′[(1E)-1,2-diethyl-1,2-ethenediyl]bis-phenol
Application:
Diethylstilbestrol is a synthetic estrogen
CAS Number:
56-53-1
Purity:
≥98%
Molecular Weight:
268.35
Molecular Formula:
C18H20O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Diethylstilbestrol is a synthetic estrogen that induces apoptosis in hormone-insensitive prostate cancer cells.


Diethylstilbestrol (CAS 56-53-1) References

  1. In utero diethylstilbestrol (DES) exposure alters Hox gene expression in the developing müllerian system.  |  Block, K., et al. 2000. FASEB J. 14: 1101-8. PMID: 10834931
  2. Continued follow-up of pregnancy outcomes in diethylstilbestrol-exposed offspring.  |  Kaufman, RH., et al. 2000. Obstet Gynecol. 96: 483-9. PMID: 11004345
  3. Low dose effect of in utero exposure to bisphenol A and diethylstilbestrol on female mouse reproduction.  |  Honma, S., et al. 2002. Reprod Toxicol. 16: 117-22. PMID: 11955942
  4. Prenatal diethylstilbestrol (DES) exposure is associated with uterine leiomyoma development.  |  Baird, DD. and Newbold, R. 2005. Reprod Toxicol. 20: 81-4. PMID: 15808789
  5. Adverse effects of the model environmental estrogen diethylstilbestrol are transmitted to subsequent generations.  |  Newbold, RR., et al. 2006. Endocrinology. 147: S11-7. PMID: 16690809
  6. Urogenital abnormalities in men exposed to diethylstilbestrol in utero: a cohort study.  |  Palmer, JR., et al. 2009. Environ Health. 8: 37. PMID: 19689815
  7. Exposure to diethylstilbestrol during sensitive life stages: a legacy of heritable health effects.  |  Reed, CE. and Fenton, SE. 2013. Birth Defects Res C Embryo Today. 99: 134-46. PMID: 23897597
  8. Current perspective of diethylstilbestrol (DES) exposure in mothers and offspring.  |  Al Jishi, T. and Sergi, C. 2017. Reprod Toxicol. 71: 71-77. PMID: 28461243
  9. Reduced fertility in female mice exposed transplacentally to diethylstilbestrol (DES).  |  McLachlan, JA., et al. 1982. Fertil Steril. 38: 364-71. PMID: 7117561
  10. Long-term effects on the female mouse genital tract associated with prenatal exposure to diethylstilbestrol.  |  McLachlan, JA., et al. 1980. Cancer Res. 40: 3988-99. PMID: 7193511
  11. Reproductive and gynecologic surgical experience in diethylstilbestrol-exposed daughters.  |  Herbst, AL., et al. 1981. Am J Obstet Gynecol. 141: 1019-28. PMID: 7315913
  12. Teratogen update: carcinogenesis and teratogenesis associated with exposure to diethylstilbestrol (DES) in utero.  |  Mittendorf, R. 1995. Teratology. 51: 435-45. PMID: 7502243
  13. Breast cancer in mothers prescribed diethylstilbestrol in pregnancy. Further follow-up.  |  Colton, T., et al. 1993. JAMA. 269: 2096-100. PMID: 8468763
  14. Induction of apoptosis by diethylstilbestrol in hormone-insensitive prostate cancer cells.  |  Robertson, CN., et al. 1996. J Natl Cancer Inst. 88: 908-17. PMID: 8656443
  15. Prostate enlargement in mice due to fetal exposure to low doses of estradiol or diethylstilbestrol and opposite effects at high doses.  |  vom Saal, FS., et al. 1997. Proc Natl Acad Sci U S A. 94: 2056-61. PMID: 9050904

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Diethylstilbestrol, 1 g

sc-204720
1 g
$71.00

Diethylstilbestrol, 5 g

sc-204720A
5 g
$287.00

Diethylstilbestrol, 25 g

sc-204720B
25 g
$547.00

Diethylstilbestrol, 50 g

sc-204720C
50 g
$1098.00

Diethylstilbestrol, 100 g

sc-204720D
100 g
$2185.00