ILPIP Inhibitors
ILPIP inhibitors target and inhibit the activity of the ILPIP protein, also known as Inhibitor of IL-1β Post-Translational Modification. ILPIP is an enzyme that plays a crucial role in the post-translational modification of the interleukin-1β (IL-1β) protein, a key mediator in inflammatory responses. The function of ILPIP involves the regulation of IL-1β maturation and secretion, which are critical in the body's immune response. The structure of ILPIP is characterized by specific domains that facilitate its enzymatic activity, including the recognition and modification of IL-1β. The ability of ILPIP to modulate IL-1β activity makes it a target of interest for the development of inhibitors that can specifically interact with and inhibit its function, thereby influencing the IL-1β mediated pathways.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $66.00 $101.00 $143.00 | 85 | |
An alkylating agent that can form cross-links in DNA, thereby potentially inhibiting DNA transcription and replication. | ||||||
Puromycin | 53-79-2 | sc-205821 sc-205821A | 10 mg 25 mg | $166.00 $322.00 | 436 | |
A compound that causes premature chain termination during translation, thereby inhibiting protein synthesis. | ||||||
Anisomycin | 22862-76-6 | sc-3524 sc-3524A | 5 mg 50 mg | $99.00 $259.00 | 36 | |
Inhibits peptide bond formation by binding to the 60S ribosomal subunit, which can suppress protein synthesis. | ||||||
Mycophenolic acid | 24280-93-1 | sc-200110 sc-200110A | 100 mg 500 mg | $69.00 $266.00 | 8 | |
Inhibits inosine monophosphate dehydrogenase, leading to decreased purine synthesis and potentially reduced RNA synthesis. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $275.00 $474.00 $1639.00 $2497.00 $5344.00 | 4 | |
A natural product that has been shown to inhibit translation initiation, potentially reducing protein expression. | ||||||
Homoharringtonine | 26833-87-4 | sc-202652 sc-202652A sc-202652B | 1 mg 5 mg 10 mg | $52.00 $125.00 $182.00 | 11 | |
Inhibits protein synthesis at the initial elongation step, which could lead to reduced expression of proteins. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Blocks N-linked glycosylation and can lead to ER stress, possibly affecting overall protein synthesis including ILPIP. | ||||||
Blasticidin S Hydrochloride | 3513-03-9 | sc-204655A sc-204655 | 25 mg 100 mg | $367.00 $520.00 | 20 | |
A nucleoside compound that inhibits peptide bond formation at the ribosome, leading to inhibition of protein synthesis. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Disrupts protein transport by blocking the exchange of protein secretion, which may influence protein expression. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $39.00 $59.00 $104.00 $206.00 | 8 | |
Binds to Hsp90 affecting its function, which can lead to the degradation of client proteins and inhibition of their expression. | ||||||