HuC inhibitors belong to a distinctive chemical class renowned for their profound impact on cellular processes involving the HuC protein. HuC, short for Hu-antigen C, is a member of the Hu family of RNA-binding proteins, which play a crucial role in the regulation of gene expression. These inhibitors are meticulously designed molecules aimed at modulating the activity of HuC, ultimately influencing the intricate dance of genetic information within cells. Structurally, HuC inhibitors often feature intricate arrangements of functional groups and chemical motifs that enable specific interactions with the target protein. These compounds typically possess high binding affinity for HuC, disrupting its normal functions and impeding its ability to bind to RNA molecules with precision.
The mechanistic underpinnings of HuC inhibitors involve their interference with HuC-mediated post-transcriptional processes. By perturbing the normal functioning of HuC, these inhibitors can influence RNA stability, processing, and translation. This class of compounds has garnered significant attention in molecular biology research due to unveil new insights into the complex regulatory networks governing gene expression. Scientists leverage HuC inhibitors as powerful tools to dissect the nuanced molecular mechanisms underlying cellular activities and uncover the intricacies of RNA biology
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol can modulate mRNA stability through its action on RNA-binding proteins like HuR, which is structurally similar to HuC. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin can affect mRNA translation by modulating protein kinases and transcription factors that influence RNA-binding proteins. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin can inhibit phosphoinositide 3-kinase (PI3K), a kinase involved in mRNA translation and stability. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein can inhibit tyrosine kinases, which can influence mRNA processing events that HuC is involved in. | ||||||
Capsaicin | 404-86-4 | sc-3577 sc-3577C sc-3577D sc-3577A | 50 mg 250 mg 500 mg 1 g | $94.00 $173.00 $255.00 $423.00 | 26 | |
Capsaicin can trigger changes in intracellular calcium signaling, which can indirectly affect mRNA stability and translation. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Sulforaphane can modulate Nrf2 pathway, thus influencing the overall mRNA stability and protein translation. | ||||||
Emodin | 518-82-1 | sc-202601 sc-202601A sc-202601B | 50 mg 250 mg 15 g | $103.00 $210.00 $6132.00 | 2 | |
Emodin can modulate multiple signaling pathways like JNK and ERK pathways, which can indirectly influence HuC's functions. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $90.00 | 1 | |
Berberine can affect AMPK signaling pathway, which is known to influence mRNA translation and stability. | ||||||
Fisetin | 528-48-3 | sc-276440 sc-276440A sc-276440B sc-276440C sc-276440D | 50 mg 100 mg 500 mg 1 g 100 g | $51.00 $77.00 $102.00 $153.00 $2856.00 | 7 | |
Fisetin can inhibit mTOR signaling, a pathway known to regulate mRNA translation and stability. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG can modulate multiple signaling pathways, which can indirectly affect the functions of RNA-binding proteins like HuC. |