HSV-1 gD Activators
The class of HSV-1 gD activators comprises a diverse range of chemicals that can either directly or indirectly enhance the expression and function of the glycoprotein D (gD) of the herpes simplex virus type 1 (HSV-1). These activators can be classified based on their modes of action, illustrating the intricate interplay between host cellular pathways and viral protein regulation. One approach involves indirect activators such as SB203580, a p38 MAPK inhibitor. By modulating the p38 MAPK signaling pathway, SB203580 can positively influence the expression and function of HSV-1 gD. Forskolin, an adenylate cyclase activator, represents another indirect activator that can modulate cAMP signaling to positively impact the expression and function of HSV-1 gD. Trichostatin A, a histone deacetylase inhibitor, exemplifies a different mechanism of activation by influencing chromatin remodeling. Inhibiting histone deacetylases with Trichostatin A may positively impact the epigenetic regulation of HSV-1 gD expression, potentially enhancing its function.
A769662, an AMP-activated protein kinase (AMPK) activator, offers another indirect approach to activate HSV-1 gD by modulating AMPK signaling. Activation of AMPK by A769662 may positively impact cellular energy homeostasis, influencing the expression and function of HSV-1 gD. This highlights the role of cellular energy pathways in regulating viral protein activity, offering insights into potential activator strategies. BayK8644, a calcium channel activator, represents an indirect activator that enhances calcium influx. Increased intracellular calcium levels induced by BayK8644 may positively influence host cell functions that support HSV-1 gD expression and function. Milrinone, a phosphodiesterase (PDE) inhibitor, represents an indirect approach to activate HSV-1 gD by modulating cAMP signaling. Inhibition of PDE by Milrinone may lead to elevated cAMP levels, positively influencing the expression and function of HSV-1 gD. In summary, the class of HSV-1 gD activators encompasses a diverse array of chemicals that can either directly or indirectly enhance the expression and function of this viral protein.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580, a p38 MAPK inhibitor, can indirectly activate HSV-1 gD by modulating the p38 MAPK signaling pathway. Inhibition of p38 MAPK can lead to altered cellular responses that may positively influence the expression and function of HSV-1 gD. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187, a calcium ionophore, can indirectly activate HSV-1 gD by influencing calcium-dependent cellular processes. By elevating intracellular calcium levels, A23187 may enhance host cell functions that support HSV-1 gD expression and function. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin, an adenylate cyclase activator, can indirectly activate HSV-1 gD by modulating cAMP signaling. Elevated cAMP levels, induced by Forskolin, may positively impact the expression and function of HSV-1 gD. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A, a histone deacetylase inhibitor, can indirectly activate HSV-1 gD by influencing chromatin remodeling. By inhibiting histone deacetylases, Trichostatin A may positively impact the epigenetic regulation of HSV-1 gD expression, potentially enhancing its function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002, a PI3-kinase inhibitor, can indirectly activate HSV-1 gD by modulating the PI3K-Akt signaling pathway. Inhibition of PI3-kinase by LY294002 may lead to altered cellular responses that positively influence the expression and function of HSV-1 gD. | ||||||
A-769662 | 844499-71-4 | sc-203790 sc-203790A sc-203790B sc-203790C sc-203790D | 10 mg 50 mg 100 mg 500 mg 1 g | $180.00 $726.00 $1055.00 $3350.00 $5200.00 | 23 | |
A769662, an AMP-activated protein kinase (AMPK) activator, can indirectly activate HSV-1 gD by modulating AMPK signaling. Activation of AMPK by A769662 may positively impact cellular energy homeostasis, influencing the expression and function of HSV-1 gD. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid, a derivative of vitamin A, can indirectly activate HSV-1 gD by influencing retinoic acid signaling. Retinoic acid may positively impact the expression and function of HSV-1 gD by regulating gene transcription through retinoic acid receptors. | ||||||
(±)-Bay K 8644 | 71145-03-4 | sc-203324 sc-203324A sc-203324B | 1 mg 5 mg 50 mg | $82.00 $192.00 $801.00 | ||
BayK8644, a calcium channel activator, can indirectly activate HSV-1 gD by enhancing calcium influx. Increased intracellular calcium levels induced by BayK8644 may positively influence host cell functions that support HSV-1 gD expression and function. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $97.00 $224.00 | 30 | |
8-Bromo-cAMP, a cyclic AMP analog, can indirectly activate HSV-1 gD by modulating cAMP signaling. Elevated cAMP levels induced by 8-Bromo-cAMP may positively impact the expression and function of HSV-1 gD. | ||||||
Prostratin | 60857-08-1 | sc-203422 sc-203422A | 1 mg 5 mg | $138.00 $530.00 | 24 | |
Prostratin, a protein kinase C (PKC) activator, can indirectly activate HSV-1 gD by modulating PKC signaling. Activation of PKC by Prostratin may positively impact cellular responses that influence the expression and function of HSV-1 gD. | ||||||