HoxC4 Activators
HoxC4 Activators refer to a specific category of chemical compounds that exhibit the unique ability to modulate the activity of the HoxC4 gene. The HoxC4 gene is a member of the Hox gene family, which plays a crucial role in embryonic development and the establishment of body patterns in various organisms, including humans. HoxC4, in particular, is implicated in the regulation of cell differentiation and tissue development, making it a key player in embryogenesis. The activators identified within this chemical class possess the capacity to enhance the expression or function of HoxC4, thereby influencing downstream molecular events associated with cellular differentiation and tissue specification.
Structurally, HoxC4 activators often demonstrate a specific interaction with regulatory elements of the HoxC4 gene, such as enhancers or promoter regions. This interaction may result in a conformational change in the gene, facilitating increased binding of transcription factors or other regulatory proteins, ultimately leading to heightened HoxC4 gene expression. The specificity of these activators for HoxC4 sets them apart from broader transcriptional regulators, allowing for a more targeted and nuanced modulation of cellular processes associated with embryonic development.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Acts as a derivative of vitamin A and activates HoxC4 gene expression directly by enhancing retinoic acid signaling pathways during embryonic development. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Functions as a histone deacetylase inhibitor, indirectly activating HoxC4 by modulating the acetylation status of histones associated with its gene regulation. | ||||||
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | $96.00 $292.00 | 27 | |
Inhibits Wnt signaling, indirectly activating HoxC4 by modulating pathways associated with Wnt signaling during embryonic development. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
Inhibits TGF-β receptor, indirectly activating HoxC4 expression by modulating TGF-β signaling pathways crucial for embryonic development. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $40.00 $120.00 $480.00 $2141.00 | 47 | |
Acts as a Notch signaling inhibitor, indirectly activating HoxC4 by modulating pathways involved in cell fate determination during development. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $272.00 | 18 | |
Modulates estrogen receptors, indirectly activating HoxC4 expression by impacting nuclear receptors and their role in transcriptional activation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Serves as a PI3K inhibitor, indirectly activating HoxC4 expression by modulating the PI3K pathway, a key player in various cellular processes. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Acts as a transcription inhibitor, activating HoxC4 directly by interfering with RNA synthesis and gene transcription, including those related to HoxC4. | ||||||
Gö 6976 | 136194-77-9 | sc-221684 | 500 µg | $227.00 | 8 | |
Acts as a Protein Kinase C inhibitor, indirectly activating HoxC4 expression by modulating the activity of protein kinase C in various signaling pathways. | ||||||