HoxC4 Inhibitors refer to a category of chemical compounds designed to target and modulate the activity of the HoxC4 gene. Hox genes are a family of evolutionarily conserved genes that play a fundamental role in the embryonic development of animals, including humans. They are involved in specifying the body plan and segmental identity along the anterior-posterior axis. HoxC4, in particular, is a member of the Hox family and plays a role in defining the identity of certain vertebral structures during embryogenesis. Inhibitors of HoxC4 gene activity are used in scientific research to investigate its specific functions and the consequences of altering its expression in various developmental contexts.
By inhibiting HoxC4, researchers can gain insights into its precise role in embryonic development, as well as its potential contributions to cellular differentiation and tissue formation. Understanding the functions of Hox genes, including HoxC4, is essential for unraveling the complex processes that govern morphogenesis and cellular differentiation during early development. These inhibitors serve as valuable tools for manipulating gene expression and studying the consequences of HoxC4 dysregulation in various experimental models. HoxC4 Inhibitors hold particular significance in developmental biology and genetics research. They provide a means to dissect the intricate genetic networks that underlie embryonic development, shedding light on the molecular mechanisms governing tissue patterning and differentiation. By uncovering the functions of HoxC4, researchers aim to deepen our understanding of the genetic control of development and potentially identify new targets for further investigation in the field of developmental biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A demethylating agent that may lead to the transcriptional activation of genes that are normally silenced, potentially reducing HoxC4 expression. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
Similar to 5-Azacytidine, it may alter DNA methylation patterns and affect HoxC4 gene expression indirectly. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
Binds to GC-rich DNA sequences and may interfere with the binding of transcription factors to the HoxC4 promoter. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Has been shown to inhibit the transcription of a broad range of genes and could suppress HoxC4 expression. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $269.00 $1050.00 | 26 | |
Specifically inhibits RNA polymerase II, potentially decreasing HoxC4 transcription. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor that can downregulate protein synthesis, indirectly affecting HoxC4 expression. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $259.00 | 41 | |
Inhibits cyclin-dependent kinases including those necessary for RNA polymerase II-driven transcription, potentially affecting HoxC4. | ||||||
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
Inhibits the phosphorylation of RNA polymerase II, which may lower HoxC4 gene transcription. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $69.00 | 2 | |
Known to intercalate into DNA and RNA affecting global transcription and mRNA degradation, potentially reducing HoxC4 expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
Can modulate gene expression at multiple levels and may influence HoxC4 expression. | ||||||