GTPBP9 Activators
GTPBP9 Activators is a class of compounds that indirectly modulate the function of GTPBP9, a protein that plays a critical role in G-protein signaling. The function of GTPBP9 protein could be extrapolated from the common roles of GTP-binding proteins, which often serve as molecular switches in various cellular processes. They typically cycle between an active GTP-bound state and an inactive GDP-bound state, regulating a variety of functions such as cell growth, cytoskeletal rearrangements, vesicle trafficking, and signal transduction.
Indirect activators of GTPBP9 may function by upregulating the expression of the gene encoding the GTP-binding protein, leading to an increased concentration of the protein within the cell and, thus, an increased potential for GTP binding and hydrolysis activity. Indirect activators could also modulate the activity of other proteins that interact with or regulate the GTP-binding protein, such as guanine nucleotide exchange factors (GEFs), which promote the exchange of GDP for GTP to activate the protein, or GTPase-activating proteins (GAPs), which accelerate the deactivation of the protein.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a p38 MAPK inhibitor. By inhibiting the p38 MAPK pathway, it indirectly influences GTPBP9, since this pathway regulates various aspects of cell survival and growth, including G-protein signaling. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor. By inhibiting the PI3K/Akt pathway, it indirectly impacts GTPBP9, since this pathway controls various aspects of cell survival and growth, including G-protein signaling. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, can indirectly modulate GTPBP9 by inhibiting tyrosine kinases, which are involved in the regulation of G-protein signaling. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a PI3K inhibitor. By inhibiting the PI3K/Akt pathway, it indirectly affects GTPBP9, since this pathway is known to control various aspects of cell survival and growth, including G-protein signaling. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, as a tyrosine kinase inhibitor, can indirectly modulate GTPBP9 by inhibiting tyrosine kinases, which are implicated in the control of G-protein signaling. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor that can indirectly modulate GTPBP9 by suppressing the JNK pathway, which has a part in the regulation of G-protein signaling. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin, an mTOR inhibitor, can indirectly affect GTPBP9 by inhibiting the mTOR pathway, which is known to control various aspects of cell growth and survival, including G-protein signaling. | ||||||
Tyrphostin B42 | 133550-30-8 | sc-3556 | 5 mg | $26.00 | 4 | |
AG490 is a JAK2 inhibitor that can indirectly modulate GTPBP9 by suppressing the JAK-STAT pathway. This pathway is involved in various cellular processes, including the regulation of G-protein signaling. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $62.00 $85.00 $356.00 | 155 | |
BAY 11-7082 is an IκBα phosphorylation inhibitor that can indirectly modulate GTPBP9 by suppressing the NF-κB pathway, which plays a part in controlling G-protein signaling. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
PP2 is a Src inhibitor that can indirectly affect GTPBP9 by inhibiting Src tyrosine kinases, which are involved in various cellular processes, including the regulation of G-protein signaling. | ||||||