Date published: 2026-5-26

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GlyR Antibodies

Santa Cruz Biotechnology features a diverse variety of GlyR monoclonal antibodies for research focused on understanding glycine receptors. GlyR monoclonal antibodies are compatible with multiple experimental applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Glycine receptors play a crucial role in the central nervous system as inhibitory neurotransmitter receptors, mediating synaptic transmission and contributing to the regulation of neuronal excitability. Their proper functioning is essential for various physiological processes, including motor control, sensory processing, and the modulation of pain. Dysregulation of glycine receptors has been implicated in several neurological disorders, making them a significant focus of research. Researchers can utilize GlyR monoclonal antibodies to explore receptor distribution patterns across different tissues and cell types. Advanced visualization techniques with GlyR monoclonal antibodies enable detailed examination of receptor localization and trafficking within cellular compartments. Secondary antibodies conjugated to horseradish peroxidase (HRP), phycoerythrin (PE), or fluorescein isothiocyanate (FITC) can enhance detection sensitivity in various applications. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing our understanding of glycine receptor biology and its impact on neurological health.

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GlyR Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

GlyR α1 Antibody (2E7)

sc-293498mouse IgG2a κ121-220 (h)WB, IP, ELISAm, r, h

new

(1)

GlyR α2 Antibody (C-11)

sc-398964mouse IgG1 κ371-420 (h)WB, IP, IF, IHC(P), ELISAh
2
(2)

GlyR β Antibody (D-8)

sc-365819mouse IgG1 κ412-441 (h)WB, IP, IF, ELISAm, r, h
3
(2)

GlyR β Antibody (G-1)

sc-390156mouse IgG1 κ328-497 (h)WB, IP, IF, ELISAm, r, h

new

(2)

GlyR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GlyR β Double Nickase Plasmid (h)

sc-403759-NIChGene KnockoutPuromycin0
(0)

GlyR β Double Nickase Plasmid (h2)

sc-403759-NIC-2hGene KnockoutPuromycin0
(0)

GlyR α1 Double Nickase Plasmid (h)

sc-404734-NIChGene KnockoutPuromycin0
(0)

GlyR α1 Double Nickase Plasmid (h2)

sc-404734-NIC-2hGene KnockoutPuromycin0
(0)

GlyR α2 CRISPR/Cas9 KO Plasmid (h)

sc-402179hGene KnockoutGFP0
(0)

GlyR α2 HDR Plasmid (h)

sc-402179-HDRhHomology Directed RepairPuromycin0
(0)

GlyR α2 Double Nickase Plasmid (h)

sc-402179-NIChGene KnockoutPuromycin0
(0)

GlyR α2 Double Nickase Plasmid (h2)

sc-402179-NIC-2hGene KnockoutPuromycin0
(0)

GlyR CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GlyR α1 CRISPR Activation Plasmid (h)

sc-404734-ACThGene ActivationPuro, Blast, Hygro0
(0)

GlyR α2 CRISPR Activation Plasmid (h)

sc-402179-ACThGene ActivationPuro, Blast, Hygro0
(0)

GlyR α3 CRISPR Activation Plasmid (h)

sc-403621-ACThGene ActivationPuro, Blast, Hygro0
(0)

GlyR α4 CRISPR Activation Plasmid (h)

sc-416048-ACThGene ActivationPuro, Blast, Hygro0
(0)

GlyR siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GlyR β siRNA (h)

sc-42471hGene SilencingN/A0
(0)

GlyR β shRNA Plasmid (h)

sc-42471-SHhGene SilencingPuromycin0
(0)

GlyR β shRNA (h) Lentiviral Particles

sc-42471-VhGene SilencingPuromycin0
(0)

GlyR β siRNA (m)

sc-42472mGene SilencingN/A0
(0)

GlyR β shRNA Plasmid (m)

sc-42472-SHmGene SilencingPuromycin0
(0)

GlyR β shRNA (m) Lentiviral Particles

sc-42472-VmGene SilencingPuromycin0
(0)

GlyR α1 siRNA (h)

sc-42467hGene SilencingN/A0
(0)

GlyR α1 shRNA Plasmid (h)

sc-42467-SHhGene SilencingPuromycin0
(0)

GlyR α1 shRNA (h) Lentiviral Particles

sc-42467-VhGene SilencingPuromycin0
(0)

GlyR α1 siRNA (m)

sc-42468mGene SilencingN/A0
(0)

GlyR α1 shRNA Plasmid (m)

sc-42468-SHmGene SilencingPuromycin0
(0)

GlyR α1 shRNA (m) Lentiviral Particles

sc-42468-VmGene SilencingPuromycin0
(0)

GlyR α2 siRNA (h)

sc-35499hGene SilencingN/A0
(0)

GlyR α2 shRNA Plasmid (h)

sc-35499-SHhGene SilencingPuromycin0
(0)

GlyR α2 shRNA (h) Lentiviral Particles

sc-35499-VhGene SilencingPuromycin0
(0)

GlyR α2 siRNA (m)

sc-35500mGene SilencingN/A0
(0)

GlyR α2 shRNA Plasmid (m)

sc-35500-SHmGene SilencingPuromycin0
(0)

GlyR α2 shRNA (m) Lentiviral Particles

sc-35500-VmGene SilencingPuromycin0
(0)

GlyR α3 siRNA (h)

sc-42469hGene SilencingN/A0
(0)

GlyR α3 shRNA Plasmid (h)

sc-42469-SHhGene SilencingPuromycin0
(0)

GlyR α3 shRNA (h) Lentiviral Particles

sc-42469-VhGene SilencingPuromycin0
(0)

GlyR α3 siRNA (m)

sc-42470mGene SilencingN/A0
(0)

GlyR α3 shRNA Plasmid (m)

sc-42470-SHmGene SilencingPuromycin0
(0)

GlyR α3 shRNA (m) Lentiviral Particles

sc-42470-VmGene SilencingPuromycin0
(0)