Date published: 2026-4-25

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GlyR α Antibodies

Santa Cruz Biotechnology offers a broad range of GlyR α monoclonal antibodies for research focused on glycine receptor signaling. GlyR α monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). GlyR α, a subunit of the glycine receptor, plays a crucial role in mediating inhibitory neurotransmission in the central nervous system. Its proper functioning is essential for maintaining the balance between excitatory and inhibitory signals, which is vital for normal motor control and sensory processing. Dysregulation of GlyR α has been implicated in various neurological disorders, making it an important target for therapeutic research. Understanding GlyR α function and regulation can provide valuable insights into potential treatment strategies for neurological conditions. Investigating GlyR α expression patterns helps reveal its distribution across different neural tissues and cell types. Studying GlyR α interactions with other proteins enhances our knowledge of synaptic transmission mechanisms. Santa Cruz Biotechnology monoclonal antibodies for GlyR α support researchers worldwide in advancing neuroscience and contributing to potential therapeutic breakthroughs.

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GlyR α Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

GlyR α1 Antibody (2E7)

sc-293498mouse IgG2a κ121-220 (h)WB, IP, ELISAm, r, h

new

(1)

GlyR α2 Antibody (C-11)

sc-398964mouse IgG1 κ371-420 (h)WB, IP, IF, IHC(P), ELISAh
2
(2)

GlyR α CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GlyR α1 Double Nickase Plasmid (h)

sc-404734-NIChGene KnockoutPuromycin0
(0)

GlyR α1 Double Nickase Plasmid (h2)

sc-404734-NIC-2hGene KnockoutPuromycin0
(0)

GlyR α2 CRISPR/Cas9 KO Plasmid (h)

sc-402179hGene KnockoutGFP0
(0)

GlyR α2 HDR Plasmid (h)

sc-402179-HDRhHomology Directed RepairPuromycin0
(0)

GlyR α2 Double Nickase Plasmid (h)

sc-402179-NIChGene KnockoutPuromycin0
(0)

GlyR α2 Double Nickase Plasmid (h2)

sc-402179-NIC-2hGene KnockoutPuromycin0
(0)

GlyR α CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GlyR α1 CRISPR Activation Plasmid (h)

sc-404734-ACThGene ActivationPuro, Blast, Hygro0
(0)

GlyR α2 CRISPR Activation Plasmid (h)

sc-402179-ACThGene ActivationPuro, Blast, Hygro0
(0)

GlyR α3 CRISPR Activation Plasmid (h)

sc-403621-ACThGene ActivationPuro, Blast, Hygro0
(0)

GlyR α4 CRISPR Activation Plasmid (h)

sc-416048-ACThGene ActivationPuro, Blast, Hygro0
(0)

GlyR α siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

GlyR α1 siRNA (h)

sc-42467hGene SilencingN/A0
(0)

GlyR α1 shRNA Plasmid (h)

sc-42467-SHhGene SilencingPuromycin0
(0)

GlyR α1 shRNA (h) Lentiviral Particles

sc-42467-VhGene SilencingPuromycin0
(0)

GlyR α1 (h)-PR

sc-42467-PRhPrimerN/A0
(0)

GlyR α1 siRNA (m)

sc-42468mGene SilencingN/A0
(0)

GlyR α1 shRNA Plasmid (m)

sc-42468-SHmGene SilencingPuromycin0
(0)

GlyR α1 shRNA (m) Lentiviral Particles

sc-42468-VmGene SilencingPuromycin0
(0)

GlyR α1 (m)-PR

sc-42468-PRmPrimerN/A0
(0)

GlyR α2 siRNA (h)

sc-35499hGene SilencingN/A0
(0)

GlyR α2 shRNA Plasmid (h)

sc-35499-SHhGene SilencingPuromycin0
(0)

GlyR α2 shRNA (h) Lentiviral Particles

sc-35499-VhGene SilencingPuromycin0
(0)

GlyR α2 (h)-PR

sc-35499-PRhPrimerN/A0
(0)

GlyR α2 siRNA (m)

sc-35500mGene SilencingN/A0
(0)

GlyR α2 shRNA Plasmid (m)

sc-35500-SHmGene SilencingPuromycin0
(0)

GlyR α2 shRNA (m) Lentiviral Particles

sc-35500-VmGene SilencingPuromycin0
(0)

GlyR α2 (m)-PR

sc-35500-PRmPrimerN/A0
(0)

GlyR α3 siRNA (h)

sc-42469hGene SilencingN/A0
(0)

GlyR α3 shRNA Plasmid (h)

sc-42469-SHhGene SilencingPuromycin0
(0)

GlyR α3 shRNA (h) Lentiviral Particles

sc-42469-VhGene SilencingPuromycin0
(0)

GlyR α3 (h)-PR

sc-42469-PRhPrimerN/A0
(0)

GlyR α3 siRNA (m)

sc-42470mGene SilencingN/A0
(0)

GlyR α3 shRNA Plasmid (m)

sc-42470-SHmGene SilencingPuromycin0
(0)

GlyR α3 shRNA (m) Lentiviral Particles

sc-42470-VmGene SilencingPuromycin0
(0)

GlyR α3 (m)-PR

sc-42470-PRmPrimerN/A0
(0)