Date published: 2026-5-5

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General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 71 to 80 of 343 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

1,1-Methanediyl Bismethanethiosulfonate

22418-52-6sc-208706
10 mg
$307.00
1
(0)

1,1-Methanediyl Bismethanethiosulfonate serves as an effective crosslinker, facilitating the formation of robust polymer networks through thiol-disulfide exchange reactions. Its unique structure promotes rapid reaction kinetics, enabling efficient crosslinking under mild conditions. The compound's ability to form stable covalent bonds enhances mechanical properties and thermal stability in materials. Additionally, its reactivity with thiol groups allows for tailored modifications, making it a valuable tool in material science.

1,5-Diazido-3-oxapentane

24345-74-2sc-208800
1 g
$320.00
(0)

1,5-Diazido-3-oxapentane acts as a versatile crosslinker, characterized by its ability to engage in azide-alkyne cycloaddition reactions, which are highly efficient and selective. This compound's unique azide functional groups facilitate the formation of stable triazole linkages, enhancing the mechanical integrity of polymer matrices. Its reactivity allows for rapid crosslinking under mild conditions, enabling the development of materials with customized properties and improved thermal stability.

1,4-Bis-maleimidobutane

28537-70-4sc-208788
10 mg
$265.00
(0)

1,4-Bis-maleimidobutane is a robust crosslinker characterized by its maleimide groups, which engage in thiol-ene click reactions, promoting the formation of stable covalent bonds. This compound exhibits a high degree of specificity in its interactions, allowing for selective crosslinking in complex systems. Its flexible aliphatic chain enhances the mobility of the crosslinked network, while the unique reactivity of the maleimide moiety contributes to rapid reaction kinetics, making it ideal for creating durable polymeric materials.

4-(2-Bromopropionyl)phenoxyacetic acid

33254-93-2sc-252078
500 mg
$719.00
(0)

4-(2-Bromopropionyl)phenoxyacetic acid serves as an effective crosslinker, facilitating the formation of robust polymer networks through its reactive acyl halide functionality. This compound exhibits selective reactivity with nucleophiles, promoting covalent bond formation that enhances material strength and stability. Its unique structure allows for tailored interactions with various substrates, influencing the kinetics of crosslinking reactions and enabling the customization of physical properties in polymeric systems.

N-Acetyl-L-tyrosine ethyl ester monohydrate

36546-50-6sc-269703
5 g
$77.00
(0)

N-Acetyl-L-tyrosine ethyl ester monohydrate acts as a versatile crosslinker, leveraging its ester functionality to engage in transesterification reactions. This compound exhibits unique solubility characteristics, promoting compatibility with diverse polymer systems. Its aromatic structure contributes to π-π stacking interactions, enhancing network stability. Additionally, the presence of the acetyl group allows for controlled hydrolysis, enabling dynamic adjustments in crosslink density and material properties.

Dimethyl 3,3′-dithiopropionimidate dihydrochloride

38285-78-8sc-252733
100 mg
$88.00
(0)

Dimethyl 3,3'-dithiopropionimidate dihydrochloride acts as a potent crosslinker, characterized by its unique ability to form disulfide bonds, which significantly enhances the mechanical strength and elasticity of polymer networks. Its dual functional groups facilitate efficient crosslinking through nucleophilic attack, leading to rapid reaction kinetics. The compound's distinctive thiol-reactive properties enable the formation of robust, three-dimensional structures, contributing to improved stability and resilience in various applications.

N-Succinimidyl Iodoacetate

39028-27-8sc-212279
100 mg
$244.00
(0)

N-Succinimidyl Iodoacetate is a potent crosslinker characterized by its iodoacetate moiety, which enables selective and robust covalent bonding with nucleophilic sites on proteins and other biomolecules. The presence of iodine enhances the electrophilicity of the carbonyl carbon, promoting faster reaction rates. This compound exhibits excellent solubility in organic solvents, facilitating its use in diverse biochemical applications. Its unique reactivity allows for the formation of intricate networks, enabling the study of molecular interactions and structural dynamics.

N-Hydroxysuccinimidyl-4-azidobenzoate

53053-08-0sc-263835
100 mg
$138.00
(1)

N-Hydroxysuccinimidyl-4-azidobenzoate serves as a specialized crosslinker, characterized by its azide functionality that enables selective reactions with alkyne groups through click chemistry. This compound exhibits high reactivity, facilitating rapid and efficient conjugation, which is crucial for forming stable covalent bonds. Its unique structure allows for the creation of intricate networks, enhancing the mechanical properties and stability of polymer matrices. The compound's distinct pathways for crosslinking contribute to tailored material properties in various applications.

Nimustine hydrochloride

55661-38-6sc-202732
sc-202732A
250 mg
1 g
$80.00
$150.00
1
(0)

Nimustine hydrochloride, as a crosslinker, exhibits distinctive reactivity due to its electrophilic nature, facilitating robust covalent bonding with nucleophilic sites in polymers and proteins. Its unique structural features enable selective crosslinking, enhancing the stability and mechanical properties of materials. The compound's solubility characteristics and interaction dynamics with various substrates further influence its kinetics, leading to tailored reaction profiles in diverse chemical environments.

p-Azidophenacyl Bromide

57018-46-9sc-212500
1 g
$700.00
(0)

p-Azidophenacyl Bromide is a versatile crosslinker characterized by its azide functional group, which enables click chemistry reactions. This compound exhibits rapid reaction kinetics, facilitating efficient formation of covalent bonds with various nucleophiles. Its unique photochemical properties allow for light-triggered activation, providing spatial and temporal control over crosslinking processes. The resulting networks exhibit enhanced stability and tailored mechanical characteristics, making it suitable for diverse applications in material science.