Dimethyl 3,3prime-dithiopropionimidate dihydrochloride CAS: 38285-78-8
MF: C8H16N2O2S2•2HCl
MW: 309.28
A thiol-cleavable, homobifunctional amine-reactive crosslinker, 8-atom spacer arm.

Dimethyl 3,3′-dithiopropionimidate dihydrochloride (CAS 38285-78-8)

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Alternate Names: DTBP; Dimethyl 3,3′-dithio-bis(propionimidate) dihydrochloride
Application: Dimethyl 3,3′-dithiopropionimidate dihydrochloride is A thiol-cleavable, homobifunctional amine-reactive crosslinker, 8-atom spacer arm
CAS Number: 38285-78-8
Molecular Weight: 309.28
Molecular Formula: C8H16N2O2S22HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Dimethyl 3,3'-dithiopropionimidate dihydrochloride is a thiol-cleavable, homobifunctional amine-reactive crosslinker. It has been shown to react with primary amines in the pH range 7.0-10.0 to form amidine bonds.
Note that the amidine linkage preserves original primary amine (+)charge. It incorporates an 8 atom spacer arm.


References

Ruoho, A., et al., A disulfide-bridge bifunctional imidoester as a reversible cross-linking reagent. Biochem. Biophys. Res. Commun. 63, 417-423, (1975)

Appearance :
Powder
Physical State :
Solid
Solubility :
H2O: 50 mg/mL
Storage :
Desiccate at 4° C
Melting Point :
170° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
9815123
MDL Number :
MFCD00043245
SMILES :
COC(=N)CCSSCCC(=N)OC.Cl.Cl

Download SDS (MSDS)

Certificate of Analysis

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