Date published: 2026-2-3

1-800-457-3801

SCBT Portrait Logo
Seach Input

General Crosslinkers

Santa Cruz Biotechnology now offers a broad range of crosslinkers for use in various applications. Crosslinkers are versatile chemical agents that can form covalent bonds between different molecules, thus linking them together. These compounds are crucial in scientific research for stabilizing the structure of proteins, nucleic acids, and other biomolecules, allowing for more accurate studies of their functions and interactions. By creating crosslinked networks, researchers can investigate the three-dimensional structure of macromolecules, study the dynamics of complex biological systems, and enhance the durability and functionality of biomaterials. In material science, crosslinkers are used to develop polymers with improved mechanical properties, such as increased strength and resistance to solvents and heat. Additionally, they play a vital role in developing and optimizing new materials, adhesives, coatings, and composites. The ability of crosslinkers to create strong, stable bonds has also been utilized in various biochemical techniques, such as immunoprecipitation, chromatography, and mass spectrometry, where they help in isolating and identifying specific molecules from complex mixtures. Santa Cruz Biotechnology provides a wide selection of crosslinkers, each with unique properties tailored for specific research needs, ensuring researchers have the tools necessary for their studies. View detailed information on our available crosslinkers by clicking on the product name.

Items 61 to 70 of 344 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Acrylic acid N-hydroxysuccinimide ester

38862-24-7sc-233817
1 g
$109.00
2
(0)

Acrylic acid N-hydroxysuccinimide ester serves as an effective crosslinker, exhibiting a propensity for rapid reaction kinetics with nucleophiles due to its electrophilic nature. The presence of the N-hydroxysuccinimide moiety enhances its reactivity, promoting efficient formation of stable covalent bonds. This compound's unique ability to facilitate multi-point attachment allows for the creation of robust polymer networks, significantly improving mechanical properties and thermal stability in various applications.

N,N′-Carbonyldiimidazole

530-62-1sc-208070
sc-208070A
5 g
10 g
$31.00
$45.00
(0)

N,N'-Carbonyldiimidazole serves as an effective crosslinker, known for its ability to activate carboxylic acids through the formation of reactive imidazolium intermediates. This unique mechanism enhances the efficiency of coupling reactions, enabling the formation of stable amide bonds. Its high reactivity and selectivity facilitate rapid crosslinking, while its low viscosity in solution allows for easy handling and integration into various polymer systems, promoting uniform network formation.

Adipic acid dihydrazide

1071-93-8sc-257072
25 g
$107.00
1
(0)

Adipic acid dihydrazide serves as a versatile crosslinker, notable for its ability to engage in hydrazone formation, which enhances network density and structural integrity. Its bifunctional nature allows for multiple crosslinking sites, leading to intricate polymer architectures. The compound's reactivity with carbonyl groups promotes rapid crosslinking kinetics, resulting in materials with improved thermal and chemical resistance. This adaptability enables the creation of specialized composites with tailored mechanical properties.

4-Bromobutyric acid

2623-87-2sc-238793
10 g
$36.00
(0)

4-Bromobutyric acid serves as a versatile crosslinker, characterized by its ability to form covalent bonds through its carboxylic acid and bromine functionalities. The bromine atom enhances reactivity, facilitating nucleophilic substitution reactions that lead to stable crosslinked networks. Its moderate hydrophobicity allows for tailored interactions with various polymer systems, while the acid's ability to engage in esterification reactions contributes to the formation of durable, resilient materials.

1,4-Phenylene-bis-maleimide

3278-31-7sc-208795
5 g
$165.00
(0)

1,4-Phenylene-bis-maleimide acts as a versatile crosslinker, distinguished by its dual maleimide groups that enable efficient formation of covalent bonds through thiol-ene reactions. This compound exhibits unique reactivity profiles, allowing for rapid crosslinking kinetics and the creation of highly interconnected networks. Its rigid aromatic structure contributes to enhanced thermal stability and mechanical strength, making it suitable for advanced composite materials and enhancing the durability of polymer systems.

Mitomycin A

4055-39-4sc-218857
sc-218857A
sc-218857B
sc-218857C
sc-218857D
sc-218857E
sc-218857F
2.5 mg
5 mg
10 mg
50 mg
100 mg
500 mg
1 g
$357.00
$612.00
$1122.00
$4947.00
$8374.00
$34753.00
$65860.00
1
(1)

Mitomycin A, as a crosslinker, exhibits remarkable reactivity due to its ability to form covalent bonds with nucleophilic sites in DNA and proteins. Its unique quinone moiety facilitates redox cycling, generating reactive oxygen species that enhance crosslinking efficiency. The compound's rigid structure promotes specific spatial arrangements, influencing the kinetics of reaction and selectivity. Additionally, its hydrophobic characteristics can modulate interactions in various solvent systems, impacting overall reactivity.

3-Maleimidopropionic acid

7423-55-4sc-216479
1 g
$330.00
(1)

3-Maleimidopropionic acid is a versatile crosslinker known for its thiol-reactive properties, enabling the formation of stable covalent bonds with sulfhydryl groups. Its unique structure promotes efficient conjugation in bioconjugation processes, enhancing the stability of resulting complexes. The compound exhibits a favorable balance of hydrophilicity and hydrophobicity, influencing its solubility and reactivity in various environments, thus facilitating diverse applications in polymer chemistry and materials science.

1,2-Phenylene-bis-maleimide

13118-04-2sc-208752
5 g
$213.00
(0)

1,2-Phenylene-bis-maleimide acts as an effective crosslinker, characterized by its ability to form stable covalent bonds through thiol-maleimide click chemistry. This compound exhibits rapid reaction kinetics, allowing for efficient crosslinking under mild conditions. Its unique structure promotes selective interactions with thiol groups, leading to the formation of robust networks. Additionally, its rigid aromatic framework contributes to enhanced thermal stability and mechanical properties in polymer matrices.

4-Mercapto-1-butanol

14970-83-3sc-238878
sc-238878A
sc-238878B
1 g
10 g
75 g
$180.00
$819.00
$3075.00
(0)

4-Mercapto-1-butanol acts as an effective crosslinker, distinguished by its thiol functional group that facilitates the formation of disulfide bonds. This unique feature promotes robust network structures through thiol-ene click chemistry, enhancing the mechanical integrity of polymer matrices. Its hydrophilic nature aids in solubility and compatibility with various substrates, while its ability to participate in redox reactions can further fine-tune crosslinking dynamics, optimizing material properties.

4-(Diphenylhydroxymethyl)benzoic acid

19672-49-2sc-238740
1 g
$147.00
(0)

4-(Diphenylhydroxymethyl)benzoic acid functions as a versatile crosslinker, characterized by its ability to engage in hydrogen bonding and π-π interactions due to its aromatic structure. The hydroxymethyl group enhances reactivity, facilitating the formation of stable ether linkages with various substrates. Its carboxylic acid moiety contributes to strong ionic interactions, promoting the development of resilient polymer networks. This compound's unique molecular architecture allows for tailored crosslinking pathways, enhancing material properties.