Adipic acid dihydrazide CAS: 1071-93-8
MF: C6H14N4O2
MW: 174.20

Adipic acid dihydrazide (CAS 1071-93-8)

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Application: CAS: 1071-93-8, MF: C6H14N4O2, MW: 174.20, Purity: ≥99%
CAS Number: 1071-93-8
Purity: ≥99%
Molecular Weight: 174.20
Molecular Formula: C6H14N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Homobifunctional cross-linking reagent that is specific for aldehydes resulting in relatively stable hydrazone linkages. This is commonly used in the linking of glycoproteins, such as antibodies, in a site specific fashion following periodate oxidation. Oxidation and coupling may conveniently be performed at pH 5.0 due to the low pKa of the hydrazide which avoids competition by primary amines. Note that the hydrazone bond may be stabilized by selective reduction using, for example, sodium cyanoborohydride.


References

Heimgartner U, et al., Reversible and irreversible cross-linking of immunoglobulin heavy chains through their carbohydrate residues. Biochem. J. 267, 585-591, (1990)

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in Water: 100 mg/mL
Storage :
Store at -20° C
Melting Point :
180-182° C (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
66117
SMILES :
C(CCC(=O)NN)CC(=O)NN

Download SDS (MSDS)

Certificate of Analysis

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