GAK Activators
Cyclin G-associated kinase (GAK) is a serine/threonine kinase involved in various cellular processes, such as clathrin-mediated membrane trafficking, endocytosis, and viral infection. GAK Activators represent a class of chemicals that can influence the function of GAK indirectly. These compounds exert their effects through their influence on related cellular processes such as endocytosis, membrane trafficking, and cellular signaling.
Chemicals such as Forskolin, EGF, Insulin, PMA, Ionomycin, Okadaic acid, Calyculin A, Tautomycetin, Wortmannin, LY294002, Rapamycin, and PP242 can potentially influence GAK function through their effects on these processes. The effects of these chemicals on GAK function are context-dependent and may vary based on the cellular environment and other biochemical parameters.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin activates adenylyl cyclase, increasing intracellular cAMP levels. This can indirectly affect GAK by modifying cellular signaling pathways. | ||||||
Tyrphostin 47 | 122520-86-9 | sc-200543 sc-200543A | 5 mg 25 mg | $79.00 $315.00 | 4 | |
Tyrphostin 47 is a growth factor that activates a number of signaling pathways including MAPK and PI3K/Akt. These pathways can indirectly influence GAK function. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $153.00 $1224.00 $12239.00 | 82 | |
Insulin can indirectly influence GAK by affecting insulin signaling pathways, which are intimately linked to endocytosis. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a potent activator of Protein Kinase C (PKC) that can indirectly influence GAK by modulating the activity of other kinases. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $94.00 $259.00 | 2 | |
Ionomycin, a calcium ionophore, can indirectly influence GAK by triggering calcium-dependent signaling pathways. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $285.00 $520.00 $1300.00 | 78 | |
Okadaic acid is a potent inhibitor of protein phosphatases PP1 and PP2A, and can indirectly influence GAK by affecting cellular phosphorylation states. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $160.00 $750.00 | 59 | |
Calyculin A is a potent inhibitor of protein phosphatases PP1 and PP2A, and can indirectly influence GAK by affecting cellular phosphorylation states. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent and irreversible inhibitor of PI3K that can indirectly influence GAK by affecting PI3K/Akt signaling pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a potent and specific inhibitor of PI3K that can indirectly influence GAK by affecting PI3K/Akt signaling pathways. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor that can indirectly influence GAK by affecting mTOR signaling pathways. | ||||||