Date published: 2025-12-18

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Fluoresceins

Santa Cruz Biotechnology now offers a broad range of fluoresceins for use in various applications. Fluoresceins are a group of synthetic organic compounds characterized by their brilliant fluorescence under UV light, making them invaluable tools in scientific research. They are widely used as fluorescent dyes in various fields, including molecular biology, biochemistry, and environmental science. In laboratory settings, fluoresceins serve as tracers and indicators in techniques like fluorescence microscopy, flow cytometry, and fluorescence-based assays. Their ability to attach to biological molecules without disrupting their function allows researchers to study complex biological processes with high sensitivity and specificity. Moreover, fluoresceins play a critical role in studying cellular and molecular dynamics, enabling scientists to visualize and track the movement and interactions of proteins, nucleic acids, and other biomolecules within living cells. This versatility has made fluoresceins a cornerstone in the development of new analytical methods and technologies, advancing our understanding of fundamental biological mechanisms. View detailed information on our available fluoresceins by clicking on the product name.

Items 1 to 10 of 114 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

2,5-Bis-(4-aminophenyl)-1,3,4-oxadiazole

2425-95-8sc-396592
sc-396592A
1 g
5 g
$100.00
$270.00
(0)

2,5-Bis-(4-aminophenyl)-1,3,4-oxadiazole is a notable fluorescein derivative characterized by its strong photoluminescent properties. Its unique structure promotes effective π-π stacking interactions, enhancing fluorescence intensity. The compound exhibits distinct electron-donating and accepting capabilities, facilitating charge transfer processes. This behavior leads to tunable emission spectra, making it suitable for various applications in fluorescence-based detection and imaging techniques.

2′,7′-Dichlorofluorescein diacetate

2044-85-1sc-209391
sc-209391A
1 g
5 g
$138.00
$559.00
19
(2)

2',7'-Dichlorofluorescein diacetate is a fluorescent compound notable for its ability to undergo hydrolysis, converting into a highly fluorescent form upon cellular uptake. This transformation is facilitated by esterases, which cleave the acetate groups, enhancing its fluorescence intensity. The compound exhibits pH-dependent fluorescence, allowing for the investigation of cellular environments. Its unique dichlorofluorescein structure contributes to strong light absorption and distinct emission characteristics, making it a versatile tool for studying dynamic biological processes.

CFSE

150347-59-4sc-202096
25 mg
$210.00
12
(1)

CFSE, a fluorescent dye, is characterized by its ability to form stable conjugates with thiol groups, enabling selective labeling of cells. Its unique structure allows for efficient energy transfer, resulting in bright fluorescence under specific excitation wavelengths. The compound exhibits a remarkable stability in various conditions, which enhances its utility in tracking cellular dynamics. Additionally, CFSE's partitioning behavior in lipid membranes provides insights into membrane interactions and cellular uptake mechanisms.

FITC-Dextran 70

60842-46-8sc-263323
sc-263323A
100 mg
500 mg
$140.00
$446.00
13
(1)

FITC-Dextran 70 is a fluorescent conjugate that exhibits strong affinity for biological macromolecules, facilitating its use in probing cellular environments. Its dextran backbone enhances solubility and biocompatibility, while the fluorescein moiety provides high quantum yield and photostability. The compound's size allows for selective permeability studies, and its unique molecular interactions with proteins and polysaccharides enable detailed investigations into cellular processes and dynamics.

Dibenzylfluorescein

97744-44-0sc-300433
sc-300433A
5 mg
25 mg
$306.00
$656.00
6
(1)

Dibenzylfluorescein is a fluorescent compound characterized by its unique structural features that enhance its photophysical properties. The presence of dibenzyl groups increases its hydrophobicity, promoting specific interactions with lipid membranes. This compound exhibits high fluorescence quantum yield and exceptional stability under various conditions. Its distinct electronic properties allow for efficient energy transfer processes, making it suitable for studying dynamic molecular interactions and pathways in complex environments.

FlAsH-EDT2

212118-77-9sc-363644
sc-363644A
sc-363644B
25 mg
100 mg
1 g
$430.00
$1469.00
$9180.00
5
(1)

FlAsH-EDT2 is a fluorescent probe distinguished by its ability to selectively bind to specific protein motifs, facilitating the visualization of cellular processes. Its unique structure enables strong interactions with thiol groups, leading to enhanced fluorescence upon binding. This compound exhibits rapid reaction kinetics, allowing for real-time monitoring of dynamic biological events. Additionally, its robust photostability ensures reliable performance in diverse experimental conditions.

BCECF/AM

117464-70-7sc-202492
1 mg
$121.00
6
(1)

BCECF/AM is a fluorescent dye characterized by its pH-sensitive properties, allowing it to emit distinct fluorescence at varying hydrogen ion concentrations. This compound undergoes hydrolysis to release BCECF, which interacts with cellular components, enhancing its fluorescence in acidic environments. Its unique ability to permeate cell membranes and respond to intracellular pH changes makes it a valuable tool for studying cellular dynamics. The dye exhibits excellent photostability, ensuring consistent performance during imaging.

Fluorescein sodium salt

518-47-8sc-206026
sc-206026A
sc-206026B
sc-206026C
100 g
500 g
1 kg
5 kg
$52.00
$152.00
$240.00
$752.00
8
(2)

Fluorescein sodium salt is a vibrant fluorescent dye known for its exceptional solubility in water and high quantum yield, which contributes to its intense fluorescence. It exhibits strong absorption in the visible spectrum, particularly around 494 nm, and emits light at approximately 521 nm. The compound's unique structure allows for efficient energy transfer and photophysical stability, making it suitable for various applications in fluorescence microscopy and flow cytometry. Its interactions with metal ions can also lead to quenching effects, providing insights into ion concentrations in various environments.

5-Carboxyfluorescein-N-hydroxysuccinimide Ester

92557-80-7sc-210302
25 mg
$456.00
(0)

5-Carboxyfluorescein-N-hydroxysuccinimide Ester is a highly reactive fluorescent probe characterized by its ability to form stable amide bonds with primary amines. This compound features a carboxylic acid group that enhances solubility and facilitates conjugation, while the N-hydroxysuccinimide moiety promotes efficient labeling. Its fluorescence properties are influenced by pH and local environment, allowing for dynamic monitoring of molecular interactions and cellular processes.

2′,7′-Dichlorodihydrofluorescein Diacetate

4091-99-0sc-359840
sc-359840A
sc-359840B
100 mg
250 mg
500 mg
$104.00
$190.00
$328.00
40
(1)

2′,7′-Dichlorodihydrofluorescein Diacetate is a versatile fluorescent dye known for its sensitivity to reactive oxygen species. Upon cellular uptake, it is hydrolyzed to a highly fluorescent form, enabling real-time visualization of oxidative stress. The compound exhibits distinct spectral properties, with excitation and emission peaks that facilitate its use in various detection methods. Its unique structure allows for selective interactions with biomolecules, enhancing its utility in studying cellular dynamics.