Fluorescein sodium salt CAS: 518-47-8
MF: C20H10O5•2Na
MW: 376.27
A sodium salt of fluorescein.

Fluorescein sodium salt (CAS 518-47-8)

Fluorescein sodium salt | CAS 518-47-8 is rated 5.0 out of 5 by 2.
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Alternate Names: Acid Yellow 73; Uranine; Fluorescein disodium salt
Application: Fluorescein sodium salt is a sodium salt of fluorescein
CAS Number: 518-47-8
Molecular Weight: 376.27
Molecular Formula: C20H10O52Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Fluorescein sodium salt is a disodium salt of fluorescein and a noted pH sensitive fluorophore. Fluorescein sodium salt has been utilized in studies as a drug model, as a penetrating dye and also as a fluorescein tracer. Fluorescein sodium salt has also been used in vitro to quantify root dentin demineralization. Additional reported uses include microscopy, as a gain medium in dye laser use and to detect latent blood stains in vitro. Common derivatives of Fluorescein include fluorescein isothiocyanate (FITC), eosin and Rose Bengal (sc-296278) and Rose Bengal sodium salt (sc-203757)


References

1. van der Veen, M.H. and ten Bosch, J.J. 1996. Eur. J. Oral Sci. 104: 118-122. PMID: 8804899
2. Fisher, K.A., et al. 2003. Chemistry. 9: 5873-5878. PMID: 14673859
3. Xiong, Y., et al. 2010. J Fluoresc. [Epub ahead of print]. PMID: 21184258

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (500 g/l) at 20° C, ethanol (slightly soluble),Insoluble in benzene, chloroform, ether. Soluble in glacial acetic acid; also soluble in alkal i hydroxides or carbonates with a bright green fluoresence appearing red by transmitted light.
Storage :
Store at room temperature
Melting Point :
>300° C
Boiling Point :
662.6° C at 760 mmHg (Predicted)
Fluoresence :
λex 490 nm, λem 514 nm in 0.1 M Tris pH 9.0
pK Values :
pKa: 4.40 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
1
RTECS :
LM5425000
PubChem CID :
10608
Merck Index :
14: 4159
MDL Number :
MFCD00167039
EC Number :
208-253-0
Beilstein Registry :
3833041
SMILES :
C1=CC=C(C(=C1)C2=C3C=CC(=O)C=C3OC4=C2C=CC(=C4)[O-])C(=O)[O-].[Na+].[Na+]

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Certificate of Analysis

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Fluorescein sodium salt (CAS 518-47-8) Product Citations

See how others have used Fluorescein sodium salt (CAS 518-47-8). Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 22355251  Lu, H. et al. 2012. Mol. Vis. 18: 403-411.

PMID: # 22697296  Ofek, K. et al. 2012. J. Cell. Mol. Med. 16: 2736-2744.

PMID: # 32165635  Nat Commun. 11: 1339.

Citations 1 to 3 of 3 total
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Rated 5 out of 5 by from I use this for microscopy work in teaching labs I use this for microscopy work in teaching labs.
Date published: 2015-10-27
Rated 5 out of 5 by from Fluorescein sodium salt is a pH Fluorescein sodium salt is a pH-sensitive fluorophore that acts as a penetrating dye and fluorescent tracer. -SCBT Publication Review
Date published: 2015-01-09
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