FER1L5 Inhibitors
FER1L5 inhibitors includes molecules that target the PI3K/Akt pathway (Wortmannin, LY294002), a key pathway for regulating cell growth and survival, which could have implications for the function of FER1L5 if it is involved in similar cellular responses. Inhibitors like PD98059, SP600125, and SB203580 modulate the MAPK family of proteins (ERK, JNK, p38), which are integral to cellular responses to a variety of external stress signals. By influencing these pathways, such inhibitors can alter the activity of proteins that are responsive to or modulated by MAPK signaling.
Inhibitors such as U73122 and Go6983 target enzymes like phospholipase C and protein kinase C, respectively, which are pivotal in the transduction of signals from the cell surface to the inside of the cell, potentially influencing proteins that are part of these signaling cascades. PP2 and NSC23766 selectively inhibit tyrosine kinases and small GTPases like Src and Rac1, respectively, affecting signaling mechanisms that could be crucial for the regulation of FER1L5. Y-27632 and ML7 are inhibitors that affect the actin cytoskeleton by targeting Rho-associated protein kinase and MLCK, respectively, potentially impacting proteins associated with cytoskeletal dynamics. Furthermore, BAPTA-AM, by chelating intracellular calcium, can influence calcium-mediated signaling events, which could affect proteins that are regulated by calcium levels within the cell.
SEE ALSO...
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A PI3K inhibitor that can prevent the PI3K/Akt signaling pathway, which may be involved in the regulation or activation of FER1L5. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another PI3K inhibitor that can block the PI3K/Akt pathway, potentially affecting proteins like FER1L5 that are regulated by this signaling cascade. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A MEK inhibitor that can inhibit the MAPK/ERK pathway, which could be implicated in the modulation of FER1L5 activity or expression. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK that can alter the JNK signaling pathway, which may interact with or regulate proteins such as FER1L5. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor that can disrupt the p38 signaling involved in stress responses, possibly affecting proteins like FER1L5 associated with these pathways. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
A PKC inhibitor that can suppress protein kinase C activity, potentially impacting proteins like FER1L5 that may be regulated by PKC-mediated signaling. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
An Src family kinase inhibitor that can inhibit Src kinase activity, potentially affecting the function or regulation of proteins like FER1L5. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A ROCK inhibitor that can interfere with Rho-associated protein kinase signaling, which might modulate proteins such as FER1L5. | ||||||
NSC 23766 | 733767-34-5 | sc-204823 sc-204823A | 10 mg 50 mg | $148.00 $597.00 | 75 | |
A Rac1 inhibitor that can disrupt Rac1-dependent signaling pathways, potentially influencing the function of proteins like FER1L5. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $89.00 $262.00 | 13 | |
An inhibitor of myosin light chain kinase (MLCK) that can affect cytoskeletal dynamics, which may impact proteins such as FER1L5 associated with these structures. | ||||||