FCGR (Fc gamma receptor) Inhibitors
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lenalidomide | 191732-72-6 | sc-218656 sc-218656A sc-218656B | 10 mg 100 mg 1 g | $49.00 $367.00 $2030.00 | 18 | |
Lenalidomide can modulate immune cell activity. Its potential down-regulation of FcγR might be due to its broad immunomodulatory properties. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $256.00 | 18 | |
Originally used as an estrogen receptor modulator, Tamoxifen has been shown to inhibit FcγR-mediated phagocytosis. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
A potent inhibitor of phosphoinositide 3-kinases (PI3K), Wortmannin can affect FcγR-mediated signaling, impacting processes like phagocytosis and endocytosis. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
Another PI3K inhibitor, LY294002 can disrupt FcγR signaling, which is crucial for various immune cell functions. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Primarily a tyrosine kinase inhibitor, Dasatinib also affects FcγR-mediated pathways, particularly in cells like natural killer (NK) cells. | ||||||
Ibrutinib | 936563-96-1 | sc-483194 | 10 mg | $153.00 | 5 | |
As a Bruton's tyrosine kinase (BTK) inhibitor, Ibrutinib can impact B cell receptor signaling and indirectly affect FcγR functions. | ||||||
R406 | 841290-81-1 | sc-364595 sc-364595A | 2 mg 10 mg | $160.00 $370.00 | 16 | |
The active metabolite of Fostamatinib, R406 inhibits Syk kinase, which plays a role in FcγR signaling, particularly in mast cells and B cells. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
A Src family kinase inhibitor, PP2 can disrupt FcγR-mediated signaling pathways, affecting processes like antibody-dependent cellular cytotoxicity (ADCC). | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
Known primarily for its action against BCR-ABL tyrosine kinase in chronic myeloid leukemia, Imatinib can also influence FcγR signaling pathways. | ||||||
BAY 61-3606 | sc-507485 | 2 mg | $345.00 | 1 | ||
This Syk inhibitor can modulate signaling through FcγRs, impacting immune responses mediated by cells like neutrophils and macrophages. | ||||||