Molecular structure of BAY 61-3606
BAY 61-3606
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Alternate Names:
2-(7-(3,4-Dimethoxyphenyl)-imidazo[1,2-c]pyrimidin-5-ylamino)-nicotinamide, HCl
Molecular Weight:
390.4
Molecular Formula:
C20H18N6O3•HCl•H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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BAY 61-3606 References
- BAY 61-3606, CDKi, and sodium butyrate treatments alter gene expression in human vestibular schwannomas and cause cell death in vitro. | Mitra, R., et al. 2012. Ecancermedicalscience. 6: 285. PMID: 23304241
- Bay 61-3606 Sensitizes TRAIL-Induced Apoptosis by Downregulating Mcl-1 in Breast Cancer Cells. | Kim, SY., et al. 2015. PLoS One. 10: e0146073. PMID: 26720004
- The role of Syk/IĸB-α/NF-ĸB pathway activation in the reversal effect of BAY 61-3606, a selective Syk inhibitor, on hypotension and inflammation in a rat model of zymosan-induced non-septic shock. | Unsal, D., et al. 2018. Clin Exp Pharmacol Physiol. 45: 155-165. PMID: 28949404
- Amyloid-β activates NLRP3 inflammasomes by affecting microglial immunometabolism through the Syk-AMPK pathway. | Jung, ES., et al. 2022. Aging Cell. 21: e13623. PMID: 35474599
- Insights into molecular docking and dynamics to reveal therapeutic potential of natural compounds against P53 protein. | Malla, BA., et al. 2023. J Biomol Struct Dyn. 41: 8762-8781. PMID: 36281711
- Low gamma-butyrobetaine dioxygenase (BBOX1) expression as a prognostic biomarker in patients with clear cell renal cell carcinoma: a machine learning approach. | Kim, KS., et al. 2023. J Pathol Clin Res. 9: 236-248. PMID: 36864013
- Construct ceRNA Network and Risk Model of Breast Cancer Using Machine Learning Methods under the Mechanism of Cuproptosis. | Deng, J., et al. 2023. Diagnostics (Basel). 13: PMID: 36980514
- A novel prognostic signature and therapy guidance for hepatocellular carcinoma based on STEAP family. | Fu, D., et al. 2024. BMC Med Genomics. 17: 16. PMID: 38191397
- Trem2 Agonist Reprograms Foamy Macrophages to Promote Atherosclerotic Plaque Stability-Brief Report. | Patterson, MT., et al. 2024. Arterioscler Thromb Vasc Biol. 44: 1646-1657. PMID: 38695172
- Prognosis prediction and immune microenvironment features of breast cancer indicated by a cuproptosis-associated long non-coding RNA signature. | Liu, S., et al. 2024. Genes Dis. 11: 101110. PMID: 38882005
Inhibitor of:
APPL1, C230052I12Rik, C230055K05Rik, C230057M02Rik, CLEC-9A, E130012A19Rik, EG623186, Fc ε RIα, FCGR (Fc gamma receptor), GlcNAc kinase, IFFO2, IL-1RAcP, IL-7, IRF-3, IRS-4, Langerin, NIK, Olfr380, Olfr547, Olfr549, Olfr56, PRIC285, RasGRP1, SKAP55-R, Slp5, and Syk.Activator of:
DAP10, Factor B, IL-5, Tec, and TEF-3.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BAY 61-3606, 2 mg | sc-507485 | 2 mg | $345.00 |