EG240921 Activators
Ifi206, an interferon-activated gene, is predicted to play a multifaceted role in cellular processes. It is anticipated to possess DNA-binding transcription repressor activity, RNA polymerase II-specific binding, and identical protein binding activities. Additionally, Ifi206 is predicted to be involved in regulating cysteine-type endopeptidase activity, gene expression, and the innate immune response. Its subcellular localization is predicted to include the nucleolus and nucleoplasm, with a potential colocalization with the cytosol. Activation of Ifi206 involves a diverse set of chemicals with distinct mechanisms of action. Retinoic Acid directly activates Ifi206 by binding to retinoic acid receptors, enhancing its DNA-binding transcription repressor activity and triggering gene expression regulation and innate immune response. Other compounds like Curcumin, Resveratrol, and Sodium Butyrate exert indirect activation by influencing various cellular processes such as chromatin modification, amplifying Ifi206's involvement in gene expression and innate immune response regulation.
5-Aza-2'-deoxycytidine directly activates Ifi206 by inhibiting DNA methylation, providing a direct link to the regulation of gene expression. Trichostatin A, an HDAC inhibitor, indirectly activates Ifi206 by modulating chromatin structure, further contributing to its role in gene expression control. Immune activators like LPS and Poly(I:C) directly stimulate Ifi206 through toll-like receptors, enhancing its participation in innate immune response regulation. In summary, Ifi206 emerges as a key player in cellular processes, engaging in the regulation of gene expression and innate immune responses. The intricate network of chemical activators, whether direct or indirect, highlights the dynamic nature of Ifi206's activation, contributing to its diverse functions in maintaining cellular homeostasis and responding to external stimuli. The interplay of these chemicals and their specific influences on Ifi206 underline the complexity and precision involved in orchestrating the activities of this interferon-activated gene.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic Acid acts as a direct activator of Ifi206 by binding to retinoic acid receptors and enhancing DNA-binding transcription repressor activity. Its role in gene expression regulation triggers Ifi206, promoting its involvement in processes related to innate immune response and endopeptidase activity. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin, a natural compound, indirectly activates Ifi206 by influencing multiple signaling pathways. It enhances RNA polymerase II-specific binding and modulates innate immune response-related processes, indirectly amplifying Ifi206 function. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol, a polyphenol, indirectly activates Ifi206 by influencing various cellular processes. It enhances identical protein binding activity and regulates gene expression, indirectly amplifying Ifi206 function and contributing to its involvement in innate immune response regulation. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 18 | |
Sodium Butyrate serves as an indirect activator by influencing chromatin structure. It enhances DNA-binding transcription repressor activity, indirectly promoting Ifi206 and stimulating its participation in the regulation of gene expression and innate immune response. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
5-Aza-2'-deoxycytidine acts as a direct activator of Ifi206 by inhibiting DNA methylation. It enhances RNA polymerase II cis-regulatory region sequence-specific binding, directly promoting Ifi206 and triggering its involvement in gene expression regulation and innate immune response. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Trichostatin A, a histone deacetylase inhibitor, indirectly activates Ifi206 by influencing chromatin modification. It enhances identical protein binding activity and stimulates RNA polymerase II-specific binding, indirectly amplifying Ifi206 function in the regulation of gene expression and innate immune response. | ||||||
Lipopolysaccharide, E. coli O55:B5 | 93572-42-0 | sc-221855 sc-221855A sc-221855B sc-221855C | 10 mg 25 mg 100 mg 500 mg | $96.00 $166.00 $459.00 $1615.00 | 12 | |
LPS serves as a direct activator by activating Toll-like receptors. It triggers Ifi206, enhancing its involvement in innate immune response regulation and modulating gene expression. | ||||||
Polyinosinic acid - polycytidylic acid sodium salt, double-stranded | 42424-50-0 | sc-204854 sc-204854A | 10 mg 100 mg | $139.00 $650.00 | 2 | |
Poly(I:C), a synthetic analog of double-stranded RNA, acts as a direct activator by activating intracellular receptors. It stimulates Ifi206, promoting its role in innate immune response regulation and gene expression control. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580, a p38 MAPK inhibitor, indirectly activates Ifi206 by influencing signaling pathways. It enhances RNA polymerase II cis-regulatory region sequence-specific binding, indirectly promoting Ifi206 function and contributing to its involvement in the regulation of gene expression and innate immune response. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
JQ1, a BET bromodomain inhibitor, indirectly activates Ifi206 by modulating chromatin structure. It enhances identical protein binding activity and regulates gene expression, indirectly amplifying Ifi206 function and contributing to its involvement in innate immune response regulation. | ||||||