Polyinosinic acid - polycytidylic acid sodium salt, double-stranded CAS: 42424-50-0
A TLR3 (Toll-like receptor 3) agonist.

Polyinosinic acid - polycytidylic acid sodium salt, double-stranded (CAS 42424-50-0)

Polyinosinic acid - polycytidylic acid sodium salt, double-stranded | CAS 42424-50-0 is rated 5.0 out of 5 by 1.
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Alternate Names: Poly (I:C), Poly(I) • Poly(C)
Application: Polyinosinic acid - polycytidylic acid sodium salt, double-stranded is a TLR3 (Toll-like receptor 3) agonist
CAS Number: 42424-50-0
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Polyinosinic Acid • Polycytidylic Acid, Sodium Salt, Double-Stranded is a TLR3 (Toll-like receptor 3) agonist. Known to induce interferon production. Hypochromicity: ≥40% at 248 nm. Extinction coefficient = 5000 M-1cm-1 at 260 nm, pH 7.0. Agent for generation of stable, mature dendritic cells (DC) and immunostimulant.

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water, and aqueous buffer.
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
TR0175000
MDL Number :
MFCD00131984

Download SDS (MSDS)

Certificate of Analysis

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Polyinosinic acid - polycytidylic acid sodium salt, double-stranded (CAS 42424-50-0)  Product Citations

See how others have used Polyinosinic acid - polycytidylic acid sodium salt, double-stranded (CAS 42424-50-0). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 31619557  J. Virol.

Citations 1 to 1 of 1 total

What is the range of molecular weight for the Poly I:C (e.g. how many kb does it have) Thanks

Asked by: Mingzhou
Thank you for your question. This polymer is approximately 400-600 bp long (MWT ~ 270,000 - 410,000 g/mol).
Answered by: Tech Service
Date published: 2019-04-24
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Rated 5 out of 5 by from Davies Davies, JM. et al. (PubMed 26414184) reported that the viral mimetic Polyinosinic acid - polycytidylic acid alters the growth characteristics of small intestinal and colonic crypt cultures. -SCBT Publication Review
Date published: 2015-04-02
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