Date published: 2026-5-15

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DR Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of DR Antibodies for the detection and analysis of death receptor proteins. DR Antibodies are validated for multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Death receptors play a crucial role in mediating apoptosis and regulating immune responses, making them significant in cancer research and therapeutic development. Understanding the signaling pathways associated with death receptors can provide insights into disease mechanisms and potential treatment strategies. DR Antibodies enable researchers to investigate cell surface receptor expression patterns and their downstream effects. Studying death receptor pathways reveals important mechanisms in programmed cell death and cellular homeostasis. Advanced research techniques using DR Antibodies help uncover new therapeutic targets in cancer and autoimmune disorders. Investigating death receptor signaling networks contributes to understanding both normal physiological processes and disease states. Santa Cruz Biotechnology monoclonal DR Antibodies support researchers worldwide in advancing scientific discoveries related to cell death pathways and therapeutic development.

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DR Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

DR1 Antibody (D-1)

sc-515083mouse IgG1 κFL (h)WB, IP, IF, ELISAm, r, h

new

(1)

DR1 Antibody (C-8)

sc-515024mouse IgG2a κFL (h)WB, IP, IF, ELISAm, r, h

new

(0)

DR3 Antibody (B-8)

sc-374203mouse IgG2b κ387-416 (h)WB, IP, IF, IHC(P), ELISAm, r, h
3
(7)

DR3 Antibody (D3 2-1-1)

sc-53974mouse IgG1 κFL (h)WB, IP, FCM, ELISAh

new

(1)

DR4 Antibody (B-9)

sc-8411mouse IgG1 κ1-130 (h)WB, IP, IF, ELISAh
20
(11)

DR4 Antibody (B-N28)

sc-65312mouse IgG1(h)WB, IPh
2
(2)

DR4 Antibody (DR4.1)

sc-32255mouse IgG1 κFL (h)IP, IF, FCMh
4
(1)

DR5 Antibody (D-6)

sc-166624mouse IgG1 κ48-76 (h)WB, IP, IF, ELISAh
36
(14)

DR5 Antibody (MD5-1)

sc-57086A. hamster IgG(m)FCMm
2
(1)

DR5 Antibody (7F4-F8-G11)

sc-517559mouse IgG(h)WB, IFm, r, h

new

(1)

DR6 Antibody (E-4)

sc-376873mouse IgG1 κ71-220 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(2)

DR CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DR4 CRISPR/Cas9 KO Plasmid (h)

sc-400747hGene KnockoutGFP0
(0)

DR4 HDR Plasmid (h)

sc-400747-HDRhHomology Directed RepairPuromycin0
(0)

DR4 Double Nickase Plasmid (h)

sc-400747-NIChGene KnockoutPuromycin0
(0)

DR4 Double Nickase Plasmid (h2)

sc-400747-NIC-2hGene KnockoutPuromycin0
(0)

DR5 CRISPR/Cas9 KO Plasmid (h)

sc-401002hGene KnockoutGFP
1
(0)

DR5 HDR Plasmid (h)

sc-401002-HDRhHomology Directed RepairPuromycin
1
(0)

DR5 Double Nickase Plasmid (h)

sc-401002-NIChGene KnockoutPuromycin
1
(0)

DR5 Double Nickase Plasmid (h2)

sc-401002-NIC-2hGene KnockoutPuromycin
1
(0)

DR5 CRISPR/Cas9 KO Plasmid (m2)

sc-423438-KO-2m2Gene KnockoutGFP0
(0)

DR5 HDR Plasmid (m2)

sc-423438-HDR-2mHomology Directed RepairPuromycin0
(0)

DR5 Double Nickase Plasmid (m)

sc-423438-NICmGene KnockoutPuromycin0
(0)

DR6 CRISPR/Cas9 KO Plasmid (m)

sc-430122mGene KnockoutGFP0
(0)

DR6 HDR Plasmid (m)

sc-430122-HDRmHomology Directed RepairPuromycin0
(0)

DR CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DR3 CRISPR Activation Plasmid (h)

sc-403461-ACThGene ActivationPuro, Blast, Hygro0
(0)

DR4 CRISPR Activation Plasmid (h)

sc-400747-ACThGene ActivationPuro, Blast, Hygro0
(0)

DR5 CRISPR Activation Plasmid (h)

sc-401002-ACThGene ActivationPuro, Blast, Hygro
1
(0)

DR6 CRISPR Activation Plasmid (h)

sc-402038-ACThGene ActivationPuro, Blast, Hygro0
(0)

DR6 CRISPR Activation Plasmid (h2)

sc-402038-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

DR siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

DR3 siRNA (h)

sc-35216hGene SilencingN/A
7
(0)

DR3 shRNA Plasmid (h)

sc-35216-SHhGene SilencingPuromycin
7
(0)

DR3 shRNA (h) Lentiviral Particles

sc-35216-VhGene SilencingPuromycin
7
(0)

DR3 siRNA (m)

sc-35217mGene SilencingN/A
1
(0)

DR3 shRNA Plasmid (m)

sc-35217-SHmGene SilencingPuromycin
1
(0)

DR3 shRNA (m) Lentiviral Particles

sc-35217-VmGene SilencingPuromycin
1
(0)

DR4 siRNA (h)

sc-35218hGene SilencingN/A
16
(1)

DR4 shRNA Plasmid (h)

sc-35218-SHhGene SilencingPuromycin
16
(1)

DR4 shRNA (h) Lentiviral Particles

sc-35218-VhGene SilencingPuromycin
16
(1)

DR5 siRNA (h)

sc-40237hGene SilencingN/A
51
(1)

DR5 shRNA Plasmid (h)

sc-40237-SHhGene SilencingPuromycin
51
(1)

DR5 shRNA (h) Lentiviral Particles

sc-40237-VhGene SilencingPuromycin
51
(1)

DR5 siRNA (m)

sc-40238mGene SilencingN/A
2
(0)

DR5 shRNA Plasmid (m)

sc-40238-SHmGene SilencingPuromycin
2
(0)

DR5 shRNA (m) Lentiviral Particles

sc-40238-VmGene SilencingPuromycin
2
(0)

DR6 siRNA (h)

sc-35220hGene SilencingN/A
6
(0)

DR6 shRNA Plasmid (h)

sc-35220-SHhGene SilencingPuromycin
6
(0)

DR6 shRNA (h) Lentiviral Particles

sc-35220-VhGene SilencingPuromycin
6
(0)

DR6 siRNA (m)

sc-35221mGene SilencingN/A0
(0)

DR6 shRNA Plasmid (m)

sc-35221-SHmGene SilencingPuromycin0
(0)

DR6 shRNA (m) Lentiviral Particles

sc-35221-VmGene SilencingPuromycin0
(0)

DR6 siRNA (r)

sc-270479rGene SilencingN/A0
(0)

DR6 shRNA Plasmid (r)

sc-270479-SHrGene SilencingPuromycin0
(0)

DR6 shRNA (r) Lentiviral Particles

sc-270479-VrGene SilencingPuromycin0
(0)

DR Transfected Lysates

Empty Table HeaderProduct NameCATALOG #SpeciesCONTROL ANTIBODYCitationsRATING

DR5 (h): 293 Lysate

sc-110563h0
(1)