DR4 Antibody (B-N28): sc-65312
- DR4 Antibody (B-N28) is a mouse monoclonal IgG1, cited in 2 publications, provided at 100 µg/ml
- raised against recombinant TRAIL R1/Fc chimera of human origin
- recommended for detection of DR4 of human origin by WB and IP
- See DR4 (B-9): sc-8411 for DR4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for DR4 Antibody (B-N28). This work is in progress.
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DR4 Antibody (B-N28) is a mouse monoclonal IgG1 antibody that detects DR4 in human samples through western blotting (WB) and immunoprecipitation (IP) applications. DR4, also known as death receptor 4, is a member of the tumor necrosis factor receptor superfamily and plays a crucial role in mediating apoptosis, particularly in response to the cytokine TRAIL (TNF-related apoptosis-inducing ligand). Anti-DR4 antibody (B-N28) recognizes a protein essential for initiating apoptotic signaling pathways, which are vital for regulating cell death and maintaining tissue homeostasis. When TRAIL binds to DR4, a cascade of intracellular events triggers the activation of caspases, ultimately resulting in programmed cell death. This process is essential for eliminating damaged or unwanted cells, thus preventing the development of cancer and other diseases. Additionally, DR4′s interaction with TRAIL is of great interest in cancer therapy, as enhancing this pathway could promote the death of tumor cells while sparing normal cells. DR4 (B-N28) antibody serves as an invaluable tool for researchers studying apoptosis and its implications in various diseases, including cancer, making DR4 (B-N28) monoclonal antibody a critical asset in biomedical research.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
DR4 Antibody (B-N28) | sc-65312 | 100 µg/ml | $322.00 |