DPY19L1 Inhibitors
The chemical class referred to as DPY19L1 Inhibitors primarily encompasses agents that can affect DPY19L1 indirectly through their modulation of various cellular pathways or processes. For instance, Wortmannin and LY294002 are phosphoinositide 3-kinase (PI3K) inhibitors. Their capability to inhibit PI3K allows them to modulate lipid signaling and membrane dynamics, which may interfere with the membrane localization and function of DPY19L1. Likewise, SB203580, a p38 MAPK inhibitor, can disrupt cellular stress signaling and thus, can alter DPY19L1's presumptive involvement in these pathways. Blebbistatin affects non-muscle myosin II, thereby altering cell migration and adhesion, processes where DPY19L1 could have regulatory input.
Chemicals like BAPTA, Ionomycin, and DAPT intervene in calcium and Notch signaling pathways, respectively, and could affect the expression or functional state of DPY19L1. Okadaic Acid, a serine/threonine phosphatase inhibitor, offers a more general approach to alter multiple cellular pathways that may involve DPY19L1. SU11274 and PD173074 are growth factor receptor inhibitors and have to modulate growth factor signaling that might implicate DPY19L1. Fenretinide serves to modulate retinoid signaling and can have an impact on the expression levels of proteins like DPY19L1. These chemicals provide a toolkit for affecting DPY19L1 through a variety of cellular mechanisms.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
By inhibiting PI3K, Wortmannin can downregulate intracellular signaling affecting membrane-associated processes, where DPY19L1 is operational. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Inhibits PI3K and can thereby alter the lipid composition of membranes, affecting the environment where DPY19L1 operates. | ||||||
BAPTA, Free Acid | 85233-19-8 | sc-201508 sc-201508A | 100 mg 500 mg | $68.00 $267.00 | 10 | |
Calcium chelator that can modulate calcium-dependent pathways, which could alter the functional state of DPY19L1 located in the endoplasmic reticulum. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
p38 MAPK inhibitor that can disrupt cellular stress signaling, thereby affecting DPY19L1's role in these pathways. | ||||||
(±)-Blebbistatin | 674289-55-5 | sc-203532B sc-203532 sc-203532A sc-203532C sc-203532D | 5 mg 10 mg 25 mg 50 mg 100 mg | $183.00 $313.00 $464.00 $942.00 $1723.00 | 7 | |
Inhibits non-muscle myosin II, thus affecting cell migration and adhesion, processes potentially regulated by DPY19L1. | ||||||
4-Hydroxyphenylretinamide | 65646-68-6 | sc-200900 sc-200900A | 5 mg 25 mg | $104.00 $315.00 | ||
Alters retinoid signaling, which can have an impact on gene expression, affecting DPY19L1 levels and function. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Serine/threonine phosphatase inhibitor that can alter a range of cellular processes, potentially including those influenced by DPY19L1. | ||||||
Phosphoramidon | 119942-99-3 | sc-201283 sc-201283A | 5 mg 25 mg | $199.00 $632.00 | 8 | |
Neutral endopeptidase inhibitor that can modify peptide cleavage and possibly affect processes in which DPY19L1 is involved. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Calcium ionophore that disrupts calcium homeostasis and thereby influences DPY19L1, particularly if it's involved in calcium-dependent signaling. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $40.00 $120.00 $480.00 $2141.00 | 47 | |
Inhibits γ-secretase and disrupts Notch signaling, potentially affecting the pathways or cellular processes where DPY19L1 has a role. | ||||||