BAPTA, Free Acid (CAS 85233-19-8)

BAPTA, Free Acid, scientifically known as 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid, serves as a versatile chelating agent extensively employed in scientific research to sequester and eliminate metal ions from solution. This compound finds widespread applications in various research applications, due to its ability to investigate a broad range of biological processes. BAPTA, Free Acid has proven instrumental in deciphering drug mechanisms of action, exploring the biological activities of compounds, investigating the biochemical and physiological effects of substances, and studying compound pharmacodynamics. By binding and removing metal ions, BAPTA, Free Acid impacts the activity of enzymes, receptors, proteins, and even drugs. Notably, it exhibits binding affinity towards several metal ions, including calcium, magnesium, zinc, and iron. This metal ion sequestration by BAPTA, Free Acid exerts influence over various biological and biochemical processes. In particular, BAPTA′s, Free Acid high selectivity for calcium (105-fold greater affinity for Ca2+ than for Mg2+) positions it as useful for calcium signaling studies, signal transduction investigations, apoptotic cascade analysis, and neuroscience research. Notably, BAPTA, Free Acid, in its free acid form, lacks cell permeability, rendering it especially useful for manipulating extracellular calcium levels. While BAPTA, Free Acid bears resemblance to the widely known chelator EGTA (ethylene glycol bis(beta-aminoethyl ether)-N,N,N′,N′-tetraacetic acid), it boasts greater resistance to pH fluctuations and demonstrates superior efficiency in calcium uptake and release processes. Additional BAPTA chelators available:BAPTA tetrapotassium salt (sc-202076),BAPTA/AM (sc-202488),BAPTA-APM (sc-206966),BAPTA-TMFM (sc-212043),5,5i difluoro Bapta(AM) (sc-217247),5,5i difluoro Bapta(K+ Salt) (sc-217248) Bapta-FF (AM) (sc-217696),BAPTA, Tetrasodium Salt (sc-278716)