Retinoic acid finely tunes cellular differentiation and proliferation by binding to nuclear receptors, which could enhance the expression and activity of DHRS13. Peroxisome proliferators activate PPARs, leading to transcriptional changes that may encompass the upregulation of dehydrogenase/reductase enzymes, thus potentially increasing DHRS13 activity. Compounds like insulin set off a cascade of signaling pathways that shape metabolic processes, altering the expression or activity of metabolic enzymes, including DHRS13. Forskolin, through its ability to raise cAMP levels, exerts a broad influence on cellular signaling, which may promote the transcription and subsequent activity of DHRS13. Phorbol esters, by engaging protein kinase C, can trigger a signaling domino effect, modifying pathways that affect DHRS13's function and expression.
Epigallocatechin gallate (EGCG) and curcumin, through their interactions with multiple signaling pathways, might modulate transcription factors or signaling molecules, thereby altering DHRS13's activity. Resveratrol, by impacting sirtuin activity, and sulforaphane, through the activation of Nrf2, both have the capacity to influence the expression of a range of metabolic enzymes, which could include DHRS13. Further, pioglitazone, as a PPARγ agonist, and 1,1-Dimethylbiguanide, Hydrochloride, by activating AMP-activated protein kinase, can both instigate genetic and enzymatic shifts that might affect DHRS13. Niacin serves as a precursor for NAD+/NADP+, essential co-factors for dehydrogenase/reductase enzymes like DHRS13, potentially affecting its enzymatic activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid impacts cellular differentiation and proliferation, processes where DHRS13 is implicated, by binding to nuclear receptors which can influence the expression and activity of dehydrogenase/reductase enzymes. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin triggers a cascade of signaling pathways that can lead to alterations in metabolic processes, possibly upregulating the expression or activity of enzymes like DHRS13 involved in metabolism. | ||||||
Phorbol | 17673-25-5 | sc-253267 | 5 mg | $270.00 | 1 | |
By activating protein kinase C (PKC), these compounds can modulate signaling pathways that affect the function and expression of metabolic enzymes, potentially increasing DHRS13 activity. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG influences numerous signaling pathways and could modulate the expression or function of DHRS13 by affecting transcription factors or signaling molecules that regulate its activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
As a modulator of sirtuin activity, resveratrol can influence cellular processes including the expression of metabolic enzymes, which may include DHRS13. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can modulate transcription factors and signaling pathways that are responsible for the regulation of metabolic enzymes, potentially enhancing DHRS13 activity. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
This compound can activate Nrf2, a transcription factor that may upregulate the expression of certain dehydrogenase/reductase enzymes, possibly including DHRS13. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $55.00 $125.00 | 13 | |
As a PPARγ agonist, pioglitazone can influence the transcription of genes related to metabolism, potentially affecting the expression and function of DHRS13. | ||||||
1,1-Dimethylbiguanide, Hydrochloride | 1115-70-4 | sc-202000F sc-202000A sc-202000B sc-202000C sc-202000D sc-202000E sc-202000 | 10 mg 5 g 10 g 50 g 100 g 250 g 1 g | $20.00 $43.00 $63.00 $156.00 $260.00 $510.00 $31.00 | 37 | |
Metformin activates AMP-activated protein kinase (AMPK) and can alter metabolic pathways, possibly impacting the expression or activity of DHRS13. | ||||||
Nicotinic Acid | 59-67-6 | sc-205768 sc-205768A | 250 g 500 g | $62.00 $124.00 | 1 | |
Niacin can influence metabolic pathways and the activity of enzymes involved in redox reactions, such as DHRS13, by serving as a precursor for NAD+/NADP+ which are co-factors for dehydrogenase/reductase enzymes. | ||||||