Date published: 2026-1-7

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DHRS13 Activators

Retinoic acid finely tunes cellular differentiation and proliferation by binding to nuclear receptors, which could enhance the expression and activity of DHRS13. Peroxisome proliferators activate PPARs, leading to transcriptional changes that may encompass the upregulation of dehydrogenase/reductase enzymes, thus potentially increasing DHRS13 activity. Compounds like insulin set off a cascade of signaling pathways that shape metabolic processes, altering the expression or activity of metabolic enzymes, including DHRS13. Forskolin, through its ability to raise cAMP levels, exerts a broad influence on cellular signaling, which may promote the transcription and subsequent activity of DHRS13. Phorbol esters, by engaging protein kinase C, can trigger a signaling domino effect, modifying pathways that affect DHRS13's function and expression.

Epigallocatechin gallate (EGCG) and curcumin, through their interactions with multiple signaling pathways, might modulate transcription factors or signaling molecules, thereby altering DHRS13's activity. Resveratrol, by impacting sirtuin activity, and sulforaphane, through the activation of Nrf2, both have the capacity to influence the expression of a range of metabolic enzymes, which could include DHRS13. Further, pioglitazone, as a PPARγ agonist, and 1,1-Dimethylbiguanide, Hydrochloride, by activating AMP-activated protein kinase, can both instigate genetic and enzymatic shifts that might affect DHRS13. Niacin serves as a precursor for NAD+/NADP+, essential co-factors for dehydrogenase/reductase enzymes like DHRS13, potentially affecting its enzymatic activity.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid impacts cellular differentiation and proliferation, processes where DHRS13 is implicated, by binding to nuclear receptors which can influence the expression and activity of dehydrogenase/reductase enzymes.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Insulin triggers a cascade of signaling pathways that can lead to alterations in metabolic processes, possibly upregulating the expression or activity of enzymes like DHRS13 involved in metabolism.

Phorbol

17673-25-5sc-253267
5 mg
$270.00
1
(0)

By activating protein kinase C (PKC), these compounds can modulate signaling pathways that affect the function and expression of metabolic enzymes, potentially increasing DHRS13 activity.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG influences numerous signaling pathways and could modulate the expression or function of DHRS13 by affecting transcription factors or signaling molecules that regulate its activity.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

As a modulator of sirtuin activity, resveratrol can influence cellular processes including the expression of metabolic enzymes, which may include DHRS13.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Curcumin can modulate transcription factors and signaling pathways that are responsible for the regulation of metabolic enzymes, potentially enhancing DHRS13 activity.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$153.00
$292.00
$489.00
$1325.00
$8465.00
$933.00
22
(1)

This compound can activate Nrf2, a transcription factor that may upregulate the expression of certain dehydrogenase/reductase enzymes, possibly including DHRS13.

Pioglitazone

111025-46-8sc-202289
sc-202289A
1 mg
5 mg
$55.00
$125.00
13
(1)

As a PPARγ agonist, pioglitazone can influence the transcription of genes related to metabolism, potentially affecting the expression and function of DHRS13.

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$43.00
$63.00
$156.00
$260.00
$510.00
$31.00
37
(1)

Metformin activates AMP-activated protein kinase (AMPK) and can alter metabolic pathways, possibly impacting the expression or activity of DHRS13.

Nicotinic Acid

59-67-6sc-205768
sc-205768A
250 g
500 g
$62.00
$124.00
1
(1)

Niacin can influence metabolic pathways and the activity of enzymes involved in redox reactions, such as DHRS13, by serving as a precursor for NAD+/NADP+ which are co-factors for dehydrogenase/reductase enzymes.