D130037M23Rik Activators
Nopchap1, a key player in box C/D snoRNP complex assembly, functions in the nucleus and is prominently expressed in the pancreas epithelium. Predicted to enable box C/D snoRNP complex binding, it plays a crucial role in the maturation of ribosomal RNA. Activation of Nopchap1 involves a sophisticated interplay with various chemical activators targeting different cellular processes.
Chemicals like Sodium Butyrate and Resveratrol act as direct activators by promoting histone acetylation and activating SIRT1, respectively, fostering an environment conducive to efficient box C/D snoRNP complex assembly. Curcumin, through NF-κB pathway modulation, and Quercetin, by influencing MAPK signaling, upregulate Nopchap1, impacting the expression of essential components involved in box C/D snoRNP assembly. Indirect activators like 5-Azacytidine and Trichostatin A alter DNA methylation patterns and inhibit histone deacetylases, respectively, contributing to favorable conditions for efficient Nopchap1 function. In conclusion, the orchestrated activation of Nopchap1 by these diverse chemicals underscores the intricate regulatory mechanisms governing box C/D snoRNP complex assembly, revealing potential avenues for manipulating this vital cellular process.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
Enhances Nopchap1 activity by promoting histone acetylation, facilitating box C/D snoRNP complex assembly in the nucleus. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Stimulates Nopchap1 through activation of SIRT1, leading to increased box C/D snoRNP complex binding and promoting proper assembly. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Upregulates Nopchap1 by modulating the NF-κB pathway, influencing the expression of key components involved in box C/D snoRNP assembly. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $130.00 $270.00 | 37 | |
Activates Nopchap1 via histone deacetylase inhibition, promoting an environment conducive to efficient box C/D snoRNP complex binding. | ||||||
Betaine | 107-43-7 | sc-214595 sc-214595A sc-214595B sc-214595C sc-214595D sc-214595E | 50 g 100 g 250 g 1 kg 2.5 kg 5 kg | $30.00 $40.00 $55.00 $160.00 $330.00 $580.00 | 2 | |
Enhances Nopchap1 activity by influencing cellular methylation patterns, contributing to the optimal assembly of box C/D snoRNP complexes. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $43.00 $65.00 $200.00 $815.00 | 6 | |
Acts as a Nopchap1 stimulator by modulating NAD+ levels, impacting sirtuin-mediated processes involved in box C/D snoRNP assembly. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Upregulates Nopchap1 through modulation of MAPK signaling, affecting the expression of factors crucial for box C/D snoRNP complex binding. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Indirectly activates Nopchap1 by influencing DNA methylation patterns, contributing to an environment favorable for efficient box C/D snoRNP assembly. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Activates Nopchap1 through histone deacetylase inhibition, promoting an environment conducive to efficient box C/D snoRNP complex binding. | ||||||
Allyl disulfide | 2179-57-9 | sc-252359 | 25 g | $78.00 | ||
Stimulates Nopchap1 activity by modulating histone acetylation patterns, contributing to the optimal assembly of box C/D snoRNP complexes. | ||||||