Date published: 2025-12-17

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Betaine (CAS 107-43-7)

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Alternate Names:
2-(trimethylazaniumyl)acetate; Oxyneurine; N-Trimethylglycine hydroxide
Application:
Betaine is researched for its role in osmoregulation and methionine biosynthesis
CAS Number:
107-43-7
Purity:
≥98%
Molecular Weight:
117.15
Molecular Formula:
C5H11NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Betaine is a naturally occurring compound that has been of interest for its role in osmoregulation. It is an end-product of the oxidative metabolism of choline and a general methyl donor. Betaine may act to be involved in a minor pathway of methionine biosynthesis and has been used to investigate homocystinuria.


Betaine (CAS 107-43-7) References

  1. Betaine aldehyde, betaine, and choline levels in rat livers during ethanol metabolism.  |  Chern, MK., et al. 2000. Biochem Pharmacol. 60: 1629-37. PMID: 11077045
  2. Dietary betaine modifies hepatic metabolism but not renal injury in rat polycystic kidney disease.  |  Ogborn, MR., et al. 2000. Am J Physiol Gastrointest Liver Physiol. 279: G1162-8. PMID: 11093938
  3. The osmolyte betaine promotes protein misfolding and disruption of protein aggregates.  |  Natalello, A., et al. 2009. Proteins. 75: 509-17. PMID: 18951407
  4. Betaine yields from marine algal species utilized in the preparation of seaweed extracts used in agriculture.  |  Blunden, G., et al. 2010. Nat Prod Commun. 5: 581-5. PMID: 20433077
  5. Betaine removal during thermo- and mesophilic aerobic batch biodegradation of beet molasses vinasse: influence of temperature and pH on the progress and efficiency of the process.  |  Cibis, E., et al. 2011. J Environ Manage. 92: 1733-9. PMID: 21367516
  6. The metabolism and biotechnological application of betaine in microorganism.  |  Zou, H., et al. 2016. Appl Microbiol Biotechnol. 100: 3865-76. PMID: 27005411
  7. The betaine profile of cereal flours unveils new and uncommon betaines.  |  Servillo, L., et al. 2018. Food Chem. 239: 234-241. PMID: 28873565
  8. Glycine betaine rather than acting only as an osmolyte also plays a role as regulator in cellular metabolism.  |  Figueroa-Soto, CG. and Valenzuela-Soto, EM. 2018. Biochimie. 147: 89-97. PMID: 29366935
  9. Betaine in Inflammation: Mechanistic Aspects and Applications.  |  Zhao, G., et al. 2018. Front Immunol. 9: 1070. PMID: 29881379
  10. Effects of betaine supplementation on L-threonine fed-batch fermentation by Escherichia coli.  |  Su, Y., et al. 2018. Bioprocess Biosyst Eng. 41: 1509-1518. PMID: 30062600
  11. Anticataractogenic effect of betaine in chick embryo hydrocortisone-induced cataract model.  |  Duman, R., et al. 2019. Indian J Med Res. 150: 407-411. PMID: 31823923
  12. Mechanism of action and the uses betaine in pig production.  |  Fu, R., et al. 2022. J Anim Physiol Anim Nutr (Berl). 106: 528-536. PMID: 34486782
  13. Betaine attenuate chronic restraint stress-induced changes in testicular damage and oxidative stress in male mice.  |  Meng, X., et al. 2022. Reprod Biol Endocrinol. 20: 80. PMID: 35597951
  14. Guanidinoacetic acid provides superior cardioprotection to its combined use with betaine and (or) creatine in HIIT-trained rats.  |  Prokic, VZ., et al. 2022. Can J Physiol Pharmacol. 100: 772-786. PMID: 35894232
  15. Neuronally produced betaine acts via a ligand-gated ion channel to control behavioral states.  |  Hardege, I., et al. 2022. Proc Natl Acad Sci U S A. 119: e2201783119. PMID: 36413500

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Betaine, 50 g

sc-214595
50 g
$30.00

Betaine, 100 g

sc-214595A
100 g
$40.00

Betaine, 250 g

sc-214595B
250 g
$55.00

Betaine, 1 kg

sc-214595C
1 kg
$160.00

Betaine, 2.5 kg

sc-214595D
2.5 kg
$330.00

Betaine, 5 kg

sc-214595E
5 kg
$580.00