Date published: 2025-11-24

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CMTM7 Inhibitors

CMTM7 inhibitors represent a class of chemical compounds designed to specifically target the cellular protein known as CMTM7, also referred to as CKLFSF7 (Chemokine-Like Factor Superfamily 7). These inhibitors are developed primarily for research purposes to better understand the biological functions and regulatory mechanisms involving CMTM7. CMTM7 itself is a member of the CMTM family, a group of small membrane-associated proteins with a wide range of functions in various cellular processes. While the exact function of CMTM7 remains a subject of ongoing research, it is believed to play a role in immune modulation, cancer biology, and possibly viral infections.

CMTM7 inhibitors are chemical compounds designed with the intent to selectively modulate the activity or expression of CMTM7 within cells. They can be used in laboratory settings to explore the molecular mechanisms associated with CMTM7, decipher its interactions with other cellular proteins, and investigate its impact on cellular processes. Researchers employ these inhibitors to gain insights into CMTM7's roles in various biological pathways, which may include its influence on immune responses, signal transduction, or oncogenic processes. The development and utilization of CMTM7 inhibitors contribute to advancing our understanding of this enigmatic protein's biology and its relevance in health and disease contexts. Researchers use these inhibitors as valuable tools to elucidate the intricacies of CMTM7's functions and its molecular interactions, shedding light on its significance in cellular physiology and disease mechanisms.

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Items 1 to 10 of 21 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

Phosphoinositide 3-kinase (PI3K) inhibitor, blocking PI3K/AKT signaling pathway, leading to downregulation of CMTM7 expression.

Lopinavir

192725-17-0sc-207831
10 mg
$129.00
6
(1)

Lopinavir inhibits CMTM7 by disrupting its enzymatic activity, interfering with viral replication in HIV-infected cells.

Ritonavir

155213-67-5sc-208310
10 mg
$122.00
7
(1)

Ritonavir inhibits CMTM7 by binding to its active site, blocking viral protease cleavage, and halting HIV replication.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

PI3K inhibitor disrupting PI3K/AKT signaling, ultimately suppressing CMTM7 expression.

Atazanavir

198904-31-3sc-207305
5 mg
$286.00
7
(1)

Atazanavir binds to CMTM7, inhibiting the enzyme′s proteolytic function and impeding the maturation of HIV particles.

BAY 80-6946

1032568-63-0sc-503264
5 mg
$551.00
(0)

Highly selective PI3K inhibitor, inhibiting PI3K/AKT/mTOR pathway and thereby reducing CMTM7 levels.

CAL-101

870281-82-6sc-364453
10 mg
$189.00
4
(1)

PI3Kδ inhibitor impeding PI3K/AKT signaling cascade, resulting in inhibition of CMTM7 expression.

Darunavir

206361-99-1sc-218079
5 mg
$311.00
4
(1)

Darunavir is a CMTM7 inhibitor that hinders viral replication by targeting the protease enzyme, preventing HIV maturation.

AZD5363

1143532-39-1sc-503190
5 mg
$309.00
(0)

AKT kinase inhibitor disrupting AKT phosphorylation, leading to downregulation of CMTM7 transcription.

(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone

sc-501166
5 mg
$540.00
(0)

Selective AKT inhibitor targeting AKT signaling pathway, thereby suppressing CMTM7 expression.