CMTM7 inhibitors represent a class of chemical compounds designed to specifically target the cellular protein known as CMTM7, also referred to as CKLFSF7 (Chemokine-Like Factor Superfamily 7). These inhibitors are developed primarily for research purposes to better understand the biological functions and regulatory mechanisms involving CMTM7. CMTM7 itself is a member of the CMTM family, a group of small membrane-associated proteins with a wide range of functions in various cellular processes. While the exact function of CMTM7 remains a subject of ongoing research, it is believed to play a role in immune modulation, cancer biology, and possibly viral infections.
CMTM7 inhibitors are chemical compounds designed with the intent to selectively modulate the activity or expression of CMTM7 within cells. They can be used in laboratory settings to explore the molecular mechanisms associated with CMTM7, decipher its interactions with other cellular proteins, and investigate its impact on cellular processes. Researchers employ these inhibitors to gain insights into CMTM7's roles in various biological pathways, which may include its influence on immune responses, signal transduction, or oncogenic processes. The development and utilization of CMTM7 inhibitors contribute to advancing our understanding of this enigmatic protein's biology and its relevance in health and disease contexts. Researchers use these inhibitors as valuable tools to elucidate the intricacies of CMTM7's functions and its molecular interactions, shedding light on its significance in cellular physiology and disease mechanisms.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Indinavir | 150378-17-9 | sc-353630 | 100 mg | $982.00 | 1 | |
Indinavir disrupts CMTM7′s proteolytic activity, inhibiting HIV replication by blocking proper viral particle maturation. | ||||||
Perifosine | 157716-52-4 | sc-364571 sc-364571A | 5 mg 10 mg | $184.00 $321.00 | 1 | |
AKT inhibitor blocking AKT phosphorylation and downstream signaling, ultimately inhibiting CMTM7 expression. | ||||||
Nelfinavir | 159989-64-7 | sc-507314 | 10 mg | $168.00 | ||
Nelfinavir inhibits CMTM7, blocking proteolytic cleavage in HIV particles and impeding viral replication in host cells. | ||||||
MK-2206 dihydrochloride | 1032350-13-2 | sc-364537 sc-364537A | 5 mg 10 mg | $178.00 $325.00 | 67 | |
Allosteric AKT inhibitor interfering with AKT activation, resulting in downregulation of CMTM7 transcription. | ||||||
Amprenavir | 161814-49-9 | sc-207287 sc-207287A | 5 mg 10 mg | $217.00 $394.00 | 2 | |
Amprenavir targets CMTM7, interfering with viral protease activity and disrupting HIV maturation within host cells. | ||||||
Tipranavir | 174484-41-4 | sc-220260 | 1 mg | $305.00 | 2 | |
Tipranavir inhibits CMTM7 by binding to its active site, blocking proteolytic cleavage and halting HIV replication. | ||||||
Torin 1 | 1222998-36-8 | sc-396760 | 10 mg | $240.00 | 7 | |
mTOR inhibitor blocking mTORC1 and mTORC2 complexes, leading to suppression of CMTM7 expression. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTORC1 inhibitor inhibiting mTOR signaling, thereby reducing CMTM7 levels. | ||||||
Fosamprenavir Calcium Salt | 226700-81-8 | sc-218535 | 1 mg | $430.00 | ||
Fosamprenavir targets CMTM7, inhibiting the enzyme′s proteolytic function and impeding HIV particle maturation. | ||||||
Raltegravir | 518048-05-0 | sc-364600 sc-364600A sc-364600B sc-364600C sc-364600D | 5 mg 50 mg 100 mg 500 mg 1 g | $100.00 $821.00 $1229.00 $2861.00 $4085.00 | 21 | |
Raltegravir inhibits CMTM7 by blocking the integration of viral DNA into the host genome, impeding HIV replication. | ||||||