CELSR3 inhibitors belong to a distinctive class of chemical compounds that target the CELSR3 receptor, a member of the cadherin superfamily. The CELSR3 receptor, short for Cadherin EGF LAG Seven-pass G-type receptor 3, is a transmembrane protein that plays a pivotal role in cellular processes, particularly in the regulation of cell adhesion and tissue morphogenesis. The inhibitors designed to modulate CELSR3 function typically interact with specific binding sites on the receptor, affecting its signaling pathways and downstream cellular responses.
CELSR3 inhibitors is diverse, reflecting the multifaceted nature of the receptor and its involvement in intricate cellular processes. Researchers have synthesized a range of small molecules, peptides, or other compounds with the capability to selectively bind to CELSR3, thereby influencing its activity. Understanding the structural nuances of CELSR3 inhibitors is essential for elucidating their mechanism of action and optimizing their potency. These inhibitors often undergo rigorous testing to assess their efficacy and specificity in modulating CELSR3-related cellular functions. The ongoing exploration of CELSR3 inhibitors contributes to the broader field of molecular pharmacology, shedding light on the intricate interplay of cellular signaling pathways and providing valuable insights for potential applications in various scientific domains.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Niclosamide | 50-65-7 | sc-250564 sc-250564A sc-250564B sc-250564C sc-250564D sc-250564E | 100 mg 1 g 10 g 100 g 1 kg 5 kg | $38.00 $79.00 $188.00 $520.00 $1248.00 $5930.00 | 8 | |
An antihelminthic drug that can inhibit Wnt/β-catenin signaling. | ||||||
JW 55 | 664993-53-7 | sc-364517 sc-364517A | 10 mg 50 mg | $172.00 $726.00 | ||
A selective inhibitor of the PARP domain of tankyrases 1 and 2, which play a crucial role in regulating the Wnt/β-catenin pathway. | ||||||
XAV939 | 284028-89-3 | sc-296704 sc-296704A sc-296704B | 1 mg 5 mg 50 mg | $36.00 $117.00 $525.00 | 26 | |
Another tankyrase inhibitor that can suppress Wnt/β-catenin signaling. | ||||||
IWR-1-endo | 1127442-82-3 | sc-295215 sc-295215A | 5 mg 10 mg | $82.00 $135.00 | 19 | |
An inhibitor of the Wnt response, working by stabilizing Axin, a negative regulator of the pathway. | ||||||
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | $96.00 $292.00 | 27 | |
An inhibitor of Wnt production, potentially blocking the pathway upstream. | ||||||
PKF118-310 | 84-82-2 | sc-364590 sc-364590A | 5 mg 25 mg | $180.00 $651.00 | ||
An inhibitor of β-catenin and TCF4 interaction, thus blocking Wnt signaling. | ||||||
Cercosporin | 35082-49-6 | sc-255013 | 5 mg | $459.00 | 1 | |
Another inhibitor of β-catenin and TCF4 interaction, thus blocking Wnt signaling. | ||||||
IQ-1 | 331001-62-8 | sc-202665 | 10 mg | $180.00 | 2 | |
A selective inhibitor of JNK, which is involved in non-canonical Wnt signaling. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Another JNK inhibitor, potentially affecting non-canonical Wnt signaling. | ||||||
β-Catenin/Tcf Inhibitor, FH535 | 108409-83-2 | sc-221398 sc-221398A | 10 mg 50 mg | $182.00 $374.00 | 7 | |
An inhibitor of both Wnt/β-catenin and PPAR signaling. | ||||||