Date published: 2026-5-4

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CELSR3 Inhibitors

CELSR3 inhibitors belong to a distinctive class of chemical compounds that target the CELSR3 receptor, a member of the cadherin superfamily. The CELSR3 receptor, short for Cadherin EGF LAG Seven-pass G-type receptor 3, is a transmembrane protein that plays a pivotal role in cellular processes, particularly in the regulation of cell adhesion and tissue morphogenesis. The inhibitors designed to modulate CELSR3 function typically interact with specific binding sites on the receptor, affecting its signaling pathways and downstream cellular responses.

CELSR3 inhibitors is diverse, reflecting the multifaceted nature of the receptor and its involvement in intricate cellular processes. Researchers have synthesized a range of small molecules, peptides, or other compounds with the capability to selectively bind to CELSR3, thereby influencing its activity. Understanding the structural nuances of CELSR3 inhibitors is essential for elucidating their mechanism of action and optimizing their potency. These inhibitors often undergo rigorous testing to assess their efficacy and specificity in modulating CELSR3-related cellular functions. The ongoing exploration of CELSR3 inhibitors contributes to the broader field of molecular pharmacology, shedding light on the intricate interplay of cellular signaling pathways and providing valuable insights for potential applications in various scientific domains.

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Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Niclosamide

50-65-7sc-250564
sc-250564A
sc-250564B
sc-250564C
sc-250564D
sc-250564E
100 mg
1 g
10 g
100 g
1 kg
5 kg
$38.00
$79.00
$188.00
$520.00
$1248.00
$5930.00
8
(1)

An antihelminthic drug that can inhibit Wnt/β-catenin signaling.

JW 55

664993-53-7sc-364517
sc-364517A
10 mg
50 mg
$172.00
$726.00
(0)

A selective inhibitor of the PARP domain of tankyrases 1 and 2, which play a crucial role in regulating the Wnt/β-catenin pathway.

XAV939

284028-89-3sc-296704
sc-296704A
sc-296704B
1 mg
5 mg
50 mg
$36.00
$117.00
$525.00
26
(1)

Another tankyrase inhibitor that can suppress Wnt/β-catenin signaling.

IWR-1-endo

1127442-82-3sc-295215
sc-295215A
5 mg
10 mg
$82.00
$135.00
19
(1)

An inhibitor of the Wnt response, working by stabilizing Axin, a negative regulator of the pathway.

IWP-2

686770-61-6sc-252928
sc-252928A
5 mg
25 mg
$96.00
$292.00
27
(1)

An inhibitor of Wnt production, potentially blocking the pathway upstream.

PKF118-310

84-82-2sc-364590
sc-364590A
5 mg
25 mg
$180.00
$651.00
(1)

An inhibitor of β-catenin and TCF4 interaction, thus blocking Wnt signaling.

Cercosporin

35082-49-6sc-255013
5 mg
$459.00
1
(0)

Another inhibitor of β-catenin and TCF4 interaction, thus blocking Wnt signaling.

IQ-1

331001-62-8sc-202665
10 mg
$180.00
2
(1)

A selective inhibitor of JNK, which is involved in non-canonical Wnt signaling.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

Another JNK inhibitor, potentially affecting non-canonical Wnt signaling.

β-Catenin/Tcf Inhibitor, FH535

108409-83-2sc-221398
sc-221398A
10 mg
50 mg
$182.00
$374.00
7
(1)

An inhibitor of both Wnt/β-catenin and PPAR signaling.