Date published: 2026-2-14

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Cdk1 Inhibitors

The chemical class referred to as Cdk1 inhibitors encompasses a diverse group of compounds that have been intricately designed to modulate the activity of Cyclin-Dependent Kinase 1 (CDK1), a key regulator of the cell cycle responsible for governing the transition from the G2 phase to the M phase. These inhibitors are meticulously developed through a combination of molecular insights, structural analyses, and mechanistic understanding, often involving advanced techniques such as computational modeling, high-throughput screening, and synthetic chemistry. The primary objective is to engineer compounds with precision to selectively target CDK1, potentially influencing its role in orchestrating the complex and tightly regulated processes of cell cycle progression and mitotic division. By targeting CDK1, these inhibitors serve as indispensable tools for investigating and deciphering the intricate molecular mechanisms that underlie cell cycle control, shedding light on the nuanced dynamics that guide cellular replication and proliferation. The exploration of Cdk1 inhibitors contributes to a deeper understanding of the finely tuned molecular interactions within the cell cycle machinery, offering insights into the delicate balance that ensures proper cellular replication and division.

Items 1 to 10 of 26 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$259.00
41
(3)

Flavopiridol (CAS 146426-40-6) is a potent inhibitor of Cdk1, a key regulator of cell cycle progression. It modulates Cdk1 activity, impacting cell division dynamics.

Roscovitine

186692-46-6sc-24002
sc-24002A
1 mg
5 mg
$94.00
$265.00
42
(2)

Roscovitine (CAS 186692-46-6) acts as a Cdk1 inhibitor, regulating cell cycle progression by modulating Cdk1 activity during mitosis.

Purvalanol A

212844-53-6sc-224244
sc-224244A
1 mg
5 mg
$72.00
$297.00
4
(2)

This compound is a potent and selective CDK1 inhibitor that has been extensively used to study cell cycle progression and mitosis.

RO-3306

872573-93-8sc-358700
sc-358700A
sc-358700B
1 mg
5 mg
25 mg
$66.00
$163.00
$326.00
37
(1)

RO-3306 (CAS 872573-93-8) is a selective Cdk1 inhibitor that halts cell cycle progression at the G2/M transition by blocking Cdk1 activity.

Kenpaullone

142273-20-9sc-200643
sc-200643A
sc-200643B
sc-200643C
1 mg
5 mg
10 mg
25 mg
$61.00
$153.00
$231.00
$505.00
1
(1)

Kenpaullone (CAS 142273-20-9) functions as a Cdk1 inhibitor, affecting cell cycle progression by modulating Cdk1 activity during crucial phases.

Flavopiridol Hydrochloride

131740-09-5sc-207687
10 mg
$317.00
(2)

Flavopiridol Hydrochloride (CAS 131740-09-5) acts as a Cdk1 inhibitor, regulating cell cycle progression by modulating Cdk1 activity during critical cellular events.

SU 9516

377090-84-1sc-222330
sc-222330A
5 mg
25 mg
$124.00
$391.00
3
(1)

SU 9516 (CAS 377090-84-1) serves as a Cdk1 inhibitor, exerting control over cell cycle progression by modulating Cdk1 activity during essential cellular processes.

10Z-Hymenialdisine

82005-12-7sc-360987
500 µg
$210.00
(1)

10Z-Hymenialdisine (CAS 82005-12-7) functions as a Cdk1 inhibitor, influencing cell cycle progression by targeting and modulating Cdk1 activity during key cellular phases.

PKC-412

120685-11-2sc-200691
sc-200691A
1 mg
5 mg
$52.00
$114.00
10
(1)

PKC-412 (CAS 120685-11-2) acts as a Cdk1 inhibitor, impacting cell cycle progression by regulating Cdk1 activity during vital cellular processes.

NU6102

444722-95-6sc-222082
sc-222082A
1 mg
5 mg
$56.00
$124.00
3
(1)

NU6102 (CAS 444722-95-6) functions as a Cdk1 inhibitor, modulating cell cycle progression by regulating Cdk1 activity during crucial cellular events.