Date published: 2025-11-24

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Cdk1 Inhibitors

The chemical class referred to as Cdk1 inhibitors encompasses a diverse group of compounds that have been intricately designed to modulate the activity of Cyclin-Dependent Kinase 1 (CDK1), a key regulator of the cell cycle responsible for governing the transition from the G2 phase to the M phase. These inhibitors are meticulously developed through a combination of molecular insights, structural analyses, and mechanistic understanding, often involving advanced techniques such as computational modeling, high-throughput screening, and synthetic chemistry. The primary objective is to engineer compounds with precision to selectively target CDK1, potentially influencing its role in orchestrating the complex and tightly regulated processes of cell cycle progression and mitotic division. By targeting CDK1, these inhibitors serve as indispensable tools for investigating and deciphering the intricate molecular mechanisms that underlie cell cycle control, shedding light on the nuanced dynamics that guide cellular replication and proliferation. The exploration of Cdk1 inhibitors contributes to a deeper understanding of the finely tuned molecular interactions within the cell cycle machinery, offering insights into the delicate balance that ensures proper cellular replication and division.

Items 11 to 20 of 26 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

AZD 5438

602306-29-6sc-361115
sc-361115A
10 mg
50 mg
$205.00
$865.00
(0)

AZD 5438 (CAS 602306-29-6) acts as a Cdk1 inhibitor, influencing cell cycle progression by modulating Cdk1 activity during essential cellular phases.

Indirubin-3′-monoxime

160807-49-8sc-202660
sc-202660A
sc-202660B
1 mg
5 mg
50 mg
$77.00
$315.00
$658.00
1
(1)

Indirubin-3'-monoxime (CAS 160807-49-8) serves as a Cdk1 inhibitor, impacting cell cycle progression by targeting and modulating Cdk1 activity during crucial cellular phases.

PHA 767491 hydrochloride

942425-68-5sc-204187
sc-204187A
10 mg
50 mg
$194.00
$786.00
3
(2)

This compound is a selective CDK1 inhibitor that has been used to study CDK1-mediated processes in cell cycle regulation.

Olomoucine II

500735-47-7sc-202750
sc-202750A
1 mg
5 mg
$138.00
$204.00
(0)

Olomoucine II (CAS 500735-47-7) acts as a Cdk1 inhibitor, influencing cell cycle progression by modulating Cdk1 activity during essential cellular phases.

5-Iodo-Indirubin-3′-monoxime

sc-221754
1 mg
$106.00
(0)

5-Iodo-Indirubin-3'-monoxime serves as a Cdk1 inhibitor, impacting cell cycle progression by targeting and modulating Cdk1 activity during essential cellular phases.

Oxindole I

sc-222104
10 mg
$273.00
2
(0)

Oxindole I acts as a Cdk1 inhibitor, influencing cell cycle progression by modulating Cdk1 activity during essential cellular phases.

Cdk1/5 Inhibitor

40254-90-8sc-202094
sc-202094A
sc-202094B
1 mg
5 mg
10 mg
$61.00
$204.00
$367.00
2
(1)

Cdk1/5 Inhibitor (CAS 40254-90-8) serves as a dual inhibitor of Cdk1 and Cdk5, impacting cell cycle progression by modulating the activities of these key regulatory kinases during essential cellular phases.

Butyrolactone I

87414-49-1sc-201533
sc-201533A
200 µg
1 mg
$120.00
$504.00
1
(0)

Butyrolactone I (CAS 87414-49-1) functions as a Cdk1 inhibitor, influencing cell cycle progression by targeting and modulating Cdk1 activity during crucial cellular phases.

N9-Isopropyl-olomoucine

158982-15-1sc-202264
sc-202264A
1 mg
5 mg
$181.00
$650.00
1
(0)

N9-Isopropyl-olomoucine (CAS 158982-15-1) acts as a Cdk1 inhibitor, influencing cell cycle progression by targeting and modulating Cdk1 activity during essential cellular phases.

NU2058

161058-83-9sc-202744
sc-202744A
5 mg
25 mg
$66.00
$321.00
2
(1)

NU2058 (CAS 161058-83-9) serves as a Cdk1 inhibitor, impacting cell cycle progression by modulating Cdk1 activity during essential cellular phases.