Calcium Channel Modulators
Items 31 to 40 of 167 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Amiloride | 2609-46-3 | sc-337527 | 1 g | $296.00 | 7 | |
Amiloride functions as a calcium channel modulator by interacting with specific sites on ion channels, particularly influencing sodium and calcium transport. Its unique structure allows for competitive inhibition, altering the conformational states of the channels. This modulation affects the influx of calcium ions, impacting cellular excitability and signaling pathways. The compound's ability to stabilize certain channel states highlights its role in fine-tuning ion homeostasis within cells. | ||||||
Benzamil•HCl | 161804-20-2 | sc-201070 | 50 mg | $195.00 | 1 | |
Benzamil•HCl functions as a calcium channel modulator by specifically inhibiting sodium-calcium exchange mechanisms. Its unique structure allows for competitive binding at the channel site, altering ion permeability and influencing cellular excitability. The compound's interaction with the channel's conformational states can lead to a nuanced modulation of calcium influx, impacting various signaling cascades. Additionally, its solubility characteristics facilitate diverse experimental applications in studying calcium dynamics. | ||||||
Dantrolene sodium salt | 14663-23-1 | sc-202124 | 100 mg | $74.00 | 9 | |
Dantrolene sodium salt acts as a calcium channel modulator by disrupting calcium release from the sarcoplasmic reticulum. Its unique ability to bind to ryanodine receptors alters their conformation, effectively reducing calcium ion flow into the cytoplasm. This modulation influences muscle contraction dynamics and cellular signaling pathways. The compound's stability in aqueous solutions enhances its utility in experimental settings, allowing for detailed investigations into calcium-mediated processes. | ||||||
Amiodarone Hydrochloride | 19774-82-4 | sc-291891 sc-291891A sc-291891B | 250 mg 1 g 5 g | $30.00 $53.00 $204.00 | 1 | |
Amiodarone Hydrochloride functions as a calcium channel modulator by interacting with various ion channels, particularly affecting the influx of calcium ions across cellular membranes. Its unique structure allows it to stabilize the inactivated state of voltage-gated calcium channels, thereby influencing cardiac action potentials and excitability. The compound exhibits notable lipophilicity, facilitating its integration into lipid membranes, which can alter membrane fluidity and impact cellular signaling pathways. | ||||||
Bisbenzimide H 33258 Fluorochrome, Trihydrochloride | 23491-45-4 | sc-202503 sc-202503A sc-202503B | 100 mg 250 mg 1 g | $133.00 $265.00 $525.00 | 5 | |
Bisbenzimide H 33258 Fluorochrome, Trihydrochloride acts as a calcium channel modulator by selectively binding to specific sites on calcium channels, altering their conformation and gating properties. This compound exhibits a high affinity for nucleic acids, which may influence calcium signaling indirectly through modulation of gene expression. Its fluorescent properties enable real-time monitoring of calcium dynamics, providing insights into cellular processes and interactions at the molecular level. | ||||||
Penfluridol | 26864-56-2 | sc-255410 | 50 mg | $135.00 | 1 | |
Penfluridol acts as a calcium channel modulator by selectively binding to specific sites on calcium channels, influencing their gating mechanisms. This interaction alters the kinetics of channel opening and closing, thereby modifying calcium ion flow across membranes. Its unique structural characteristics enable it to preferentially affect certain channel subtypes, leading to distinct alterations in cellular excitability and signaling pathways. The compound's dynamic behavior in various ionic environments further enhances its modulatory effects. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $28.00 $53.00 | 37 | |
2-APB functions as a calcium channel modulator by interacting with the inactivation gate of various calcium channels, leading to altered ion permeability. Its unique ability to stabilize the open state of these channels enhances calcium influx, influencing intracellular signaling pathways. Additionally, 2-APB can disrupt phospholipase C signaling, affecting downstream effects on cellular calcium homeostasis. This compound's distinct structural features allow for selective modulation of calcium-dependent processes. | ||||||
HC-030031 | 349085-38-7 | sc-203994 sc-203994A | 10 mg 50 mg | $89.00 $333.00 | 2 | |
HC-030031 functions as a calcium channel modulator through its ability to interact with the voltage-sensing domains of calcium channels, stabilizing their inactive state. This modulation affects the activation threshold and alters the duration of channel openings, impacting calcium influx. Its unique hydrophobic regions facilitate selective binding to specific channel isoforms, resulting in nuanced effects on cellular calcium homeostasis and excitability. The compound's interactions with lipid membranes also influence its modulatory efficacy. | ||||||
Lanthanum(III) chloride heptahydrate | 10025-84-0 | sc-211720 sc-211720A | 25 g 100 g | $62.00 $166.00 | ||
Lanthanum(III) chloride heptahydrate acts as a calcium channel modulator by influencing the conformational dynamics of calcium channels. Its unique coordination chemistry allows it to bind selectively to specific sites, altering channel gating mechanisms. This compound can enhance the stability of channel complexes, affecting ion permeability and cellular signaling pathways. Additionally, its hydration shell plays a crucial role in mediating interactions with membrane lipids, further modulating channel activity. | ||||||
Nicardipine hydrochloride | 54527-84-3 | sc-202731 sc-202731A | 1 g 5 g | $33.00 $83.00 | 5 | |
Nicardipine hydrochloride functions as a calcium channel modulator by selectively interacting with L-type calcium channels, stabilizing their inactive state. Its unique structure facilitates specific binding, which alters the kinetics of calcium ion influx. This compound exhibits distinct solubility characteristics, enhancing its interaction with lipid bilayers. Furthermore, its ability to form hydrogen bonds can influence the conformational states of channel proteins, impacting their regulatory mechanisms. | ||||||