Calcium Channel Modulators
Items 1 to 10 of 167 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Nemadipine-A | 54280-71-6 | sc-202727 | 5 mg | $66.00 | 3 | |
Nemadipine-A acts as a selective calcium channel modulator, exhibiting unique binding affinities that influence channel conformation and gating mechanisms. Its distinct molecular interactions with voltage-gated calcium channels alter ion permeability, impacting cellular excitability. The compound demonstrates specific reaction kinetics, characterized by rapid onset and prolonged effects, which can lead to differential modulation of calcium influx in various tissues. This specificity highlights its role in fine-tuning calcium-dependent processes. | ||||||
Diethyl Pyrocarbonate | 1609-47-8 | sc-202574B sc-202574 sc-202574A | 5 g 25 g 100 g | $61.00 $138.00 $478.00 | 1 | |
Diethyl Pyrocarbonate serves as a calcium channel modulator by selectively interacting with amino acid residues in the channel's pore region, leading to conformational changes that affect ion flow. Its reactivity with nucleophilic sites enhances its ability to modify channel dynamics, influencing calcium ion conductance. The compound's unique electrophilic nature allows for targeted modifications, resulting in distinct modulation patterns that can alter cellular signaling pathways and excitability. | ||||||
Neuropeptide Y | 90880-35-6 | sc-3140 | 0.5 mg | $97.00 | 5 | |
Neuropeptide Y functions as a calcium channel modulator by binding to specific receptors that initiate intracellular signaling cascades. This interaction influences the phosphorylation state of channel proteins, thereby altering their activity and calcium permeability. Its role in modulating neurotransmitter release is significant, as it affects synaptic plasticity and neuronal excitability. The peptide's unique structure allows for selective engagement with various calcium channels, leading to diverse physiological effects. | ||||||
9,21-Dehydroryanodine | 94513-55-0 | sc-291770 | 1 mg | $490.00 | ||
9,21-Dehydroryanodine acts as a calcium channel modulator by selectively interacting with voltage-gated calcium channels, particularly influencing their gating mechanisms. This compound alters the conformational dynamics of channel proteins, enhancing or inhibiting calcium ion flow. Its unique structural features enable it to stabilize specific channel states, thereby affecting calcium influx and downstream signaling pathways. The compound's kinetic profile reveals distinct binding affinities, contributing to its nuanced regulatory effects on cellular calcium homeostasis. | ||||||
Fasudil, Monohydrochloride Salt | 105628-07-7 | sc-203418 sc-203418A sc-203418B sc-203418C sc-203418D sc-203418E sc-203418F | 10 mg 50 mg 250 mg 1 g 2 g 5 g 10 g | $18.00 $33.00 $87.00 $168.00 $253.00 $496.00 $910.00 | 5 | |
Fasudil, Monohydrochloride Salt functions as a calcium channel modulator by targeting Rho kinase pathways, which play a crucial role in cellular signaling. Its unique ability to disrupt RhoA signaling cascades leads to altered calcium ion dynamics within cells. This compound exhibits specific interactions with calcium channels, influencing their activation thresholds and ion permeability. The modulation of these pathways results in distinct kinetic behaviors, impacting cellular responses to calcium fluctuations. | ||||||
R 568 hydrochloride | 177172-49-5 | sc-361302 sc-361302A | 10 mg 50 mg | $214.00 $877.00 | 4 | |
R 568 hydrochloride acts as a calcium channel modulator by selectively interacting with voltage-gated calcium channels, enhancing their sensitivity to membrane depolarization. This compound exhibits unique binding kinetics, which facilitate a more pronounced influx of calcium ions during excitatory stimuli. Its distinct molecular interactions can alter channel gating mechanisms, leading to modified calcium homeostasis and influencing downstream signaling pathways. The compound's behavior reflects a nuanced balance between channel activation and inactivation, contributing to its role in cellular calcium regulation. | ||||||
Ru360 | sc-222265 | 500 µg | $293.00 | 12 | ||
Ru360 functions as a calcium channel modulator by selectively inhibiting mitochondrial calcium uptake, thereby influencing intracellular calcium dynamics. Its unique interaction with the calcium uniporter alters the transport kinetics, leading to a reduction in mitochondrial calcium levels. This modulation can affect cellular energy metabolism and apoptosis pathways. The compound's specificity for mitochondrial channels highlights its distinct role in regulating calcium signaling within the cell, impacting various physiological processes. | ||||||
Amiloride hydrochloride dihydrate | 17440-83-4 | sc-364401 | 250 mg | $79.00 | 1 | |
Amiloride hydrochloride dihydrate acts as a calcium channel modulator by blocking epithelial sodium channels, which indirectly influences calcium influx. Its unique binding affinity alters ion transport dynamics, affecting cellular excitability and signaling pathways. The compound's ability to stabilize membrane potential and modulate ion homeostasis showcases its role in fine-tuning calcium-related processes, impacting various cellular functions and interactions. | ||||||
Heparin sodium salt | 9041-08-1 | sc-203075 sc-203075A sc-203075B sc-203075C sc-203075D sc-203075E sc-203075F | 250 mg 1 g 5 g 25 g 100 g 500 g 1 kg | $81.00 $209.00 $950.00 $3541.00 $14048.00 $41096.00 $70747.00 | 23 | |
Heparin sodium salt functions as a calcium channel modulator through its unique ability to interact with glycosaminoglycans, influencing calcium signaling pathways. Its structural complexity allows for specific binding to proteins involved in calcium homeostasis, thereby altering intracellular calcium levels. This modulation affects various cellular processes, including muscle contraction and neurotransmitter release, highlighting its role in regulating ion dynamics and cellular communication. | ||||||
Mibefradil dihydrochloride | 116666-63-8 | sc-204083 sc-204083A | 10 mg 50 mg | $213.00 $865.00 | 4 | |
Mibefradil dihydrochloride acts as a calcium channel modulator by selectively inhibiting T-type calcium channels, which play a crucial role in regulating cellular excitability. Its unique binding affinity alters the conformational state of these channels, impacting calcium influx and subsequent signaling cascades. This modulation can influence various physiological processes, including neuronal activity and vascular tone, showcasing its intricate role in calcium-mediated cellular functions. | ||||||