Amiloride CAS: 2609-46-3
MF: C6H8ClN7O
MW: 229.63

Amiloride (CAS 2609-46-3)

Amiloride | CAS 2609-46-3 is rated 5.0 out of 5 by 1.
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Alternate Names: Amipramidin, Midamor
CAS Number: 2609-46-3
Molecular Weight: 229.63
Molecular Formula: C6H8ClN7O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
Physical State :
Solid
Storage :
Store at 4° C
Melting Point :
185.21° C (Predicted)
Boiling Point :
~557.9° C at 760 mmHg (Predicted)
Density :
~2.1 g/cm3 (Predicted)
Refractive Index :
n20D 1.89 (Predicted)
IC50 :
ENaC : IC50 = 0.2 µM (human); αENaC: IC50 = 0.78 µM (human); MAO-A: IC50 = 3.91 µM (human); ASIC3: IC50 = 4.4 µM (human); uPA: IC50 = 7 µM (human)
Ki Data :
uPA: Ki= 2.51 µM (human); Adenosine A2A-R: Ki= 3.28 µM (human); Solute carrier family 22 member 2: Ki= 4.7 µM (rat); Solute carrier family 22 member 1: Ki= 6.9 µM (rat); Amine oxidase, copper containing: Ki= 10 µM (rat)
pK Values :
pKa: 7.81 (Predicted), pKb: 3.78 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
16231
Merck Index :
14: 406
MDL Number :
MFCD00077316
EC Number :
220-024-7
Beilstein Registry :
616612
SMILES :
C1(=C(N=C(C(=N1)Cl)N)N)C(=O)N=C(N)N

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Certificate of Analysis

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Amiloride (CAS 2609-46-3)  Product Citations

See how others have used Amiloride (CAS 2609-46-3). Click on the entry to view the PubMed entry .

Citations 1 to 7 of 7 total

PMID: # 27469139  Szymanska, M. et al. 2016. J. Cell. Mol. Med. 20: 1999-2011.

PMID: # 26239765  Sroka, IC. et al. 2016. J. Cell. Biochem. 117: 491-9.

PMID: # 27070720  Patel, K. et al. 2016. Molecular pharmaceutics. 13: 2049-58.

PMID: # 22767227  Cai, Q. et al. 2012. FASEB J. 26: 3306-20.

PMID: # 21438025  Koumakpayi, IH. et al. 2011. Mol Carcinog. -.

PMID: # 30003911  Steroids. 117-133.

PMID: # 27872138  J. Cell Biol. 667-685.

Citations 1 to 7 of 7 total
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Rated 5 out of 5 by from Relevant assays for usage as analytical standards Relevant assays for usage as analytical standards.
Date published: 2015-06-08
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