The chemical class referred to as C2CD4D Inhibitors includes a range of compounds that can indirectly influence the function of C2CD4D by modulating the calcium signaling pathways and calcium-dependent processes within cells. These compounds achieve their effects through various mechanisms, such as blocking calcium channels, inhibiting enzymes that regulate calcium homeostasis, antagonizing proteins that transduce calcium signals, and chelating intracellular calcium.
For instance, nimodipine and verapamil can reduce calcium influx through L-type calcium channels, while thapsigargin and cyclopiazonic acid can disrupt the calcium stores in the endoplasmic reticulum by inhibiting the SERCA pump, all of which can lead to alterations in C2CD4D-related signaling. Modulators like 2-APB, calmidazolium chloride, and W-7 hydrochloride can impact the function of IP3 receptors, calmodulin, and related calcium-dependent processes that can influence C2CD4D activity. KN-93's inhibition of CaMKII and ML-9's effect on myosin light-chain kinase can also affect downstream signaling processes. BAPTA-AM serves as a calcium chelator, providing a buffering effect on intracellular calcium levels, which can modulate C2CD4D-mediated pathways. SKF-96365 and xestospongin C inhibit receptor-mediated calcium entry and IP3 receptor activity, respectively, further influencing the cellular processes related to C2CD4D.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Nimodipine | 66085-59-4 | sc-201464 sc-201464A | 100 mg 1 g | $60.00 $301.00 | 2 | |
L-type calcium channel blocker that can reduce calcium influx, possibly affecting C2CD4D-related calcium-dependent signaling. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $367.00 | ||
Another calcium channel blocker that can alter intracellular calcium levels and potentially influence C2CD4D-mediated processes. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
SERCA pump inhibitor that can disrupt calcium homeostasis in the endoplasmic reticulum, potentially affecting C2CD4D activity. | ||||||
2-APB | 524-95-8 | sc-201487 sc-201487A | 20 mg 100 mg | $27.00 $52.00 | 37 | |
Modulator of IP3 receptors and store-operated channels that can influence calcium signaling, possibly impacting C2CD4D function. | ||||||
Calmidazolium chloride | 57265-65-3 | sc-201494 sc-201494A | 10 mg 50 mg | $153.00 $600.00 | 27 | |
Calmodulin inhibitor that can affect calcium signal transduction pathways, potentially altering C2CD4D activity. | ||||||
W-7 | 61714-27-0 | sc-201501 sc-201501A sc-201501B | 50 mg 100 mg 1 g | $163.00 $300.00 $1642.00 | 18 | |
Another calmodulin antagonist that can disrupt calcium-mediated signaling, possibly affecting C2CD4D. | ||||||
KN-93 | 139298-40-1 | sc-202199 | 1 mg | $178.00 | 25 | |
Inhibitor of CaMKII that can alter downstream calcium signaling, potentially influencing C2CD4D function. | ||||||
Cyclopiazonic Acid | 18172-33-3 | sc-201510 sc-201510A | 10 mg 50 mg | $173.00 $612.00 | 3 | |
Inhibitor of the SERCA pump, can disrupt calcium storage and potentially impact C2CD4D-related signaling. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $449.00 | 61 | |
Calcium chelator that can buffer intracellular calcium levels, possibly affecting C2CD4D-mediated signaling pathways. | ||||||
ML-9 | 105637-50-1 | sc-200519 sc-200519A sc-200519B sc-200519C | 10 mg 50 mg 100 mg 250 mg | $110.00 $440.00 $660.00 $1200.00 | 2 | |
Inhibitor of myosin light-chain kinase that can affect cytoskeleton dynamics and calcium signaling, potentially influencing C2CD4D. |