BOULE Inhibitors
BOULE inhibitors are a category of chemical compounds that have gained prominence in the fields of molecular biology and pharmacology due to their role in modulating specific cellular processes. BOULE is a protein known for its essential function in the development of germ cells, particularly in male gametogenesis. This protein is part of the DAZ (Deleted in Azoospermia) family and plays a pivotal role in the meiotic process, which is critical for the formation of spermatozoa. BOULE inhibitors are designed to interact with the active site or binding domain of the BOULE protein, effectively inhibiting its function and influencing cellular processes associated with germ cell development and meiosis.
Structurally, BOULE inhibitors are engineered to selectively target the active site of BOULE, ensuring high specificity for this particular protein. By inhibiting BOULE, these compounds may disrupt its role in the meiotic process, which can have profound implications for spermatogenesis and male fertility. The study of BOULE inhibitors is of significant interest to researchers as it provides insights into the regulatory mechanisms governing essential cellular functions in the male reproductive system.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ketoconazole | 65277-42-1 | sc-200496 sc-200496A | 50 mg 500 mg | $63.00 $265.00 | 21 | |
As an antifungal agent, it inhibits steroid synthesis and might indirectly affect hormonal regulation impacting BOULE expression. | ||||||
Busulfan | 55-98-1 | sc-204658 | 10 g | $49.00 | 3 | |
Alkylating agent could affect cell division and indirectly influence BOULE expression in germ cells. | ||||||
Flutamide | 13311-84-7 | sc-204757 sc-204757A sc-204757D sc-204757B sc-204757C | 1 g 5 g 25 g 500 g 1 kg | $47.00 $156.00 $171.00 $525.00 $941.00 | 4 | |
A nonsteroidal antiandrogen, potentially affecting androgen signaling and indirectly BOULE expression. | ||||||
Bicalutamide | 90357-06-5 | sc-202976 sc-202976A | 100 mg 500 mg | $42.00 $146.00 | 27 | |
Similar to Flutamide, could modulate androgen receptor activity, potentially influencing BOULE expression. | ||||||
Spironolactone | 52-01-7 | sc-204294 | 50 mg | $109.00 | 3 | |
A diuretic with antiandrogenic properties, might indirectly affect hormonal pathways and BOULE expression. | ||||||
Cimetidine | 51481-61-9 | sc-202996 sc-202996A | 5 g 10 g | $62.00 $86.00 | 1 | |
A histamine H2-receptor antagonist, known to have antiandrogenic effects, potentially influencing BOULE expression. | ||||||
Finasteride | 98319-26-7 | sc-203954 | 50 mg | $105.00 | 3 | |
Inhibits 5-alpha-reductase, affecting dihydrotestosterone levels, potentially impacting BOULE expression. | ||||||
Dutasteride | 164656-23-9 | sc-207600 | 10 mg | $167.00 | 2 | |
Similar to Finasteride, but more potent, might influence BOULE expression through hormonal modulation. | ||||||
MDV3100 | 915087-33-1 | sc-364354 sc-364354A | 5 mg 50 mg | $245.00 $1051.00 | 7 | |
A more potent antiandrogen, could affect androgen receptor signaling and indirectly impact BOULE expression. | ||||||
Tamoxifen | 10540-29-1 | sc-208414 | 2.5 g | $272.00 | 18 | |
As a selective estrogen receptor modulator, it could influence hormonal balance, potentially affecting BOULE expression. | ||||||