Date published: 2026-4-24

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Biglycan Inhibitors

Biglycan Inhibitors is a chemical class characterized by molecules that exhibit the ability to modulate the activity or function of biglycan, a proteoglycan protein found in the extracellular matrix of various tissues in the human body. Biglycan is part of a family of small leucine-rich proteoglycans (SLRPs) and plays a crucial role in maintaining tissue structure and function. Inhibitors belonging to this class are designed to interact with biglycan in a way that can alter its biological effects. The chemical compounds within the Biglycan Inhibitors class often possess unique molecular structures that enable them to interact with biglycan, either by binding to it directly or by interfering with its signaling pathways. These inhibitors can serve as valuable research tools for scientists studying the biology of biglycan and its role in various physiological and pathological processes. Understanding how these inhibitors influence biglycan's function can shed light on the underlying mechanisms of tissue homeostasis and provide insights into avenues for further investigation in various scientific fields, such as cell biology, tissue engineering, and regenerative medicine. Researchers utilize Biglycan Inhibitors to explore the intricacies of biglycan's molecular interactions and unravel its biological significance, ultimately contributing to a deeper understanding of extracellular matrix biology.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

SB 431542

301836-41-9sc-204265
sc-204265A
sc-204265B
1 mg
10 mg
25 mg
$82.00
$216.00
$416.00
48
(1)

May inhibit biglycan expression by blocking TGF-β signaling, a known regulator of biglycan.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

Potentially decreases biglycan expression by blocking NF-κB signaling, which is involved in inflammatory responses.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

May affect biglycan expression by altering histone acetylation and chromatin structure.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

Might downregulate biglycan by inhibiting the PI3K/Akt pathway.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Could potentially decrease biglycan expression through the inhibition of the mTOR signaling pathway.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

May inhibit biglycan expression by blocking MAPK/ERK signaling.

SB-216763

280744-09-4sc-200646
sc-200646A
1 mg
5 mg
$71.00
$202.00
18
(1)

Might affect biglycan levels by inhibiting GSK-3β activity.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Could potentially decrease biglycan expression by inhibiting p38 MAPK signaling pathway.

17-AAG

75747-14-7sc-200641
sc-200641A
1 mg
5 mg
$67.00
$156.00
16
(2)

May affect biglycan expression by inhibiting HSP90, which plays a role in protein stability.

Stat3 inhibitor V, stattic

19983-44-9sc-202818
sc-202818A
sc-202818B
sc-202818C
sc-202818D
sc-202818E
sc-202818F
25 mg
100 mg
250 mg
500 mg
1 g
2.5 g
5 g
$130.00
$196.00
$274.00
$512.00
$731.00
$1408.00
$2091.00
114
(3)

Might downregulate biglycan by inhibiting STAT3 signaling.