Date published: 2025-12-18

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betaKlotho Activators

BetaKlotho activators constitute a unique category of chemical compounds that have been designed to interact with and modulate the activity of the betaKlotho protein. BetaKlotho, also known as KLB, is a co-receptor involved in mediating the effects of specific hormones, particularly fibroblast growth factors (FGFs). This co-receptor is a crucial component in various physiological processes, including metabolism, energy regulation, and bile acid homeostasis. BetaKlotho activators are synthesized with the aim of influencing the binding and signaling pathways associated with betaKlotho, ultimately allowing researchers to delve into the intricate molecular mechanisms and biological pathways governed by this protein.

The mechanisms of action of betaKlotho activators can vary, but their overarching purpose is to facilitate scientific exploration of betaKlotho's functions within the context of cellular and metabolic processes. By modulating betaKlotho activity, researchers can investigate its role in regulating metabolic homeostasis, energy expenditure, and other physiological functions. This research can offer valuable insights into the intricate interplay between hormones, their receptors, and downstream signaling pathways. The study of betaKlotho activators contributes to our broader understanding of the complex web of molecular interactions underlying metabolic and endocrine regulation.

SEE ALSO...

Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Resveratrol is a natural phenol found in grapes and berries. It is thought to upregulate betaKlotho expression possibly through its antioxidant and anti-inflammatory properties.

1,1-Dimethylbiguanide, Hydrochloride

1115-70-4sc-202000F
sc-202000A
sc-202000B
sc-202000C
sc-202000D
sc-202000E
sc-202000
10 mg
5 g
10 g
50 g
100 g
250 g
1 g
$20.00
$42.00
$62.00
$153.00
$255.00
$500.00
$30.00
37
(1)

1,1-Dimethylbiguanide, Hydrochloride, a widely used antidiabetic drug, may enhance betaKlotho expression through the activation of AMPK, a cellular energy regulator.

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$65.00
$319.00
$575.00
$998.00
28
(1)

Retinoic acid, found in Vitamin A, can potentially increase betaKlotho expression. It acts through retinoic acid receptors, influencing gene expression.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$36.00
$68.00
$107.00
$214.00
$234.00
$862.00
$1968.00
47
(1)

Curcumin, a component of turmeric, is known for its anti-inflammatory effects. It may induce betaKlotho expression by modulating various signaling pathways.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Quercetin, a flavonoid found in many fruits and vegetables, might enhance betaKlotho expression due to its antioxidant properties.

Cholecalciferol

67-97-0sc-205630
sc-205630A
sc-205630B
1 g
5 g
10 g
$70.00
$160.00
$290.00
2
(1)

Vitamin D3, also known as cholecalciferol, can potentially upregulate betaKlotho. It interacts with vitamin D receptors affecting gene transcription.

Caffeine

58-08-2sc-202514
sc-202514A
sc-202514B
sc-202514C
sc-202514D
50 g
100 g
250 g
1 kg
5 kg
$32.00
$66.00
$95.00
$188.00
$760.00
13
(1)

Caffeine, a central nervous system stimulant, may influence betaKlotho expression through its impact on metabolic processes.

Berberine

2086-83-1sc-507337
250 mg
$90.00
1
(0)

Berberine, a compound found in several plants, is thought to increase betaKlotho expression, potentially through pathways related to glucose and lipid metabolism.

Genistein

446-72-0sc-3515
sc-3515A
sc-3515B
sc-3515C
sc-3515D
sc-3515E
sc-3515F
100 mg
500 mg
1 g
5 g
10 g
25 g
100 g
$26.00
$92.00
$120.00
$310.00
$500.00
$908.00
$1821.00
46
(1)

Genistein, a soy-derived isoflavone, might modulate betaKlotho expression, possibly through estrogen receptor-mediated pathways.

D,L-Sulforaphane

4478-93-7sc-207495A
sc-207495B
sc-207495C
sc-207495
sc-207495E
sc-207495D
5 mg
10 mg
25 mg
1 g
10 g
250 mg
$150.00
$286.00
$479.00
$1299.00
$8299.00
$915.00
22
(1)

DL-Sulforaphane, found in cruciferous vegetables, can potentially influence betaKlotho expression through its detoxifying and antioxidant properties.