ARMC12 Activators
Forskolin and db-cAMP are included due to their ability to raise cAMP levels, which can trigger cAMP-dependent pathways involving ARMC12. Ionomycin elevates intracellular calcium levels, stimulating ARMC12-related pathways. LY294002, by inhibiting PI3K, disrupts negative feedback mechanisms that may inhibit ARMC12, thus increasing its activity. Similarly, Okadaic Acid and Sodium Fluoride focus on the phosphatase-related controls on ARMC12; both of them inhibit phosphatase activity, thereby stabilizing ARMC12.
Retinoic Acid and 5-Azacytidine can work on the transcriptional level to upregulate ARMC12. Specifically, Retinoic Acid influences gene expression through nuclear receptors, while 5-Azacytidine inhibits DNA methyltransferases, thus affecting epigenetic control over ARMC12. EGF and PMA work through kinase-related pathways; EGF activates its receptor, which can lead to phosphorylation cascades elevating ARMC12, while PMA activates PKC, increasing ARMC12. Lastly, Resveratrol activates SIRT1, which may lead to upregulation of ARMC12, while Rottlerin's inhibition of PKC-δ could raise ARMC12 activity by affecting downstream signaling.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, enhancing cAMP levels, thereby potentially boosting ARMC12 in cAMP-dependent pathways. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $96.00 $264.00 | 2 | |
Calcium ionophore that increases intracellular calcium, potentially triggering pathways involving ARMC12. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Known to activate SIRT1, which may subsequently lead to an upregulation of ARMC12. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
Cell-permeable analog of cAMP, expected to indirectly activate ARMC12 through cAMP-dependent pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Inhibits PI3K, disrupting negative feedback mechanisms that inhibit ARMC12, thereby potentially raising its activity. | ||||||
Okadaic Acid | 78111-17-8 | sc-3513 sc-3513A sc-3513B | 25 µg 100 µg 1 mg | $291.00 $530.00 $1800.00 | 78 | |
Serine/threonine phosphatase inhibitor; could raise ARMC12 by affecting phosphorylation status. | ||||||
Sodium Fluoride | 7681-49-4 | sc-24988A sc-24988 sc-24988B | 5 g 100 g 500 g | $40.00 $46.00 $100.00 | 26 | |
Inhibits cellular phosphatases, potentially stabilizing ARMC12 through reduced dephosphorylation. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Involved in transcriptional regulation; may increase ARMC12 through gene expression modulation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates PKC; expected to increase ARMC12 through kinase pathways. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
DNA methyltransferase inhibitor; could upregulate ARMC12 through epigenetic mechanisms. | ||||||