Annexin IV Inhibitors
Annexin IV Inhibitors include a variety of compounds that can suppress or modulate the activity of Annexin IV. This class notably comprises calcium chelators like EGTA and BAPTA, which reduce the availability of calcium ions, crucial for Annexin IV's function. The presence of these chelators might inhibit the calcium-dependent binding of Annexin IV to phospholipids.
Additionally, this class incorporates phospholipase inhibitors and compounds like Neomycin, Rifampicin, Propranolol, Lidocaine, and Tetracaine, which can interact with or alter the composition of phospholipids, affecting Annexin IV's binding ability. Calcium channel blockers such as Verapamil, Nifedipine, and Diltiazem are included due to their capacity to reduce intracellular calcium levels, thereby inhibiting Annexin IV's calcium-dependent activity. Amiloride, known for its effects on ion channels, is also considered due to its impact on cellular calcium homeostasis.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
EGTA | 67-42-5 | sc-3593 sc-3593A sc-3593B sc-3593C sc-3593D | 1 g 10 g 100 g 250 g 1 kg | $21.00 $65.00 $120.00 $251.00 $815.00 | 23 | |
A calcium chelator that can lower intracellular calcium levels, potentially inhibiting Annexin IV activity due to its calcium-dependent nature. | ||||||
BAPTA/AM | 126150-97-8 | sc-202488 sc-202488A | 25 mg 100 mg | $138.00 $458.00 | 61 | |
Another calcium chelator, similar to EGTA, which can bind to calcium ions and reduce their availability for Annexin IV activation. | ||||||
Neomycin sulfate | 1405-10-3 | sc-3573 sc-3573A | 1 g 5 g | $27.00 $35.00 | 20 | |
An aminoglycoside antibiotic that can bind to phospholipids, potentially competing with Annexin IV for binding sites and inhibiting its activity. | ||||||
Rifampicin | 13292-46-1 | sc-200910 sc-200910A sc-200910B sc-200910C | 1 g 5 g 100 g 250 g | $97.00 $328.00 $676.00 $1467.00 | 6 | |
An antibiotic known to interact with phospholipids, potentially inhibiting the phospholipid-binding activity of Annexin IV. | ||||||
Propranolol | 525-66-6 | sc-507425 | 100 mg | $180.00 | ||
A non-selective beta-blocker that can interact with phospholipids, potentially affecting Annexin IV binding. | ||||||
Lidocaine | 137-58-6 | sc-204056 sc-204056A | 50 mg 1 g | $51.00 $131.00 | ||
A local anesthetic that can interact with cell membranes and phospholipids, potentially affecting Annexin IV's phospholipid-binding ability. | ||||||
Tetracaine | 94-24-6 | sc-255645 sc-255645A sc-255645B sc-255645C sc-255645D sc-255645E | 5 g 25 g 100 g 500 g 1 kg 5 kg | $66.00 $309.00 $500.00 $1000.00 $1503.00 $5000.00 | ||
Another local anesthetic that might affect Annexin IV activity by altering its interaction with phospholipids. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $374.00 | ||
A calcium channel blocker that can reduce calcium availability, potentially inhibiting Annexin IV activity. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
Similar to Verapamil, Nifedipine is a calcium channel blocker that might reduce the calcium-dependent activity of Annexin IV. | ||||||
Diltiazem | 42399-41-7 | sc-204726 sc-204726A | 1 g 5 g | $209.00 $464.00 | 4 | |
Another calcium channel blocker that could potentially inhibit Annexin IV by reducing intracellular calcium levels. | ||||||