Annexin IV Activators
The chemical class of Annexin IV Activators includes a range of compounds that can potentially stimulate or modulate the activity of Annexin IV. This class notably includes agents that can increase calcium levels, such as calcium ions themselves, calcium ionophores like A23187 and Ionophore X-537A, and Thapsigargin. Since Annexin IV's activity is calcium-dependent, the alteration of calcium levels could enhance its binding to phospholipids and activity in the cell.
Additionally, this class incorporates phospholipids like PIP2 and Phosphatidylserine, which are potential binding partners for Annexin IV. The presence of these phospholipids might enhance Annexin IV's affinity and binding to cellular membranes. Secondary messengers and signaling molecules, such as cAMP, Forskolin, and Dibutyryl-cAMP, are included due to their capacity to modulate various cellular signaling pathways, potentially influencing Annexin IV's function. Brefeldin A, known for its effects on membrane trafficking, could also indirectly affect Annexin IV activity.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Calcium | 7440-70-2 | sc-252536 | 5 g | $209.00 | ||
As Annexin IV is calcium-dependent, increasing extracellular or intracellular calcium levels could potentially enhance its activation and binding to phospholipids. | ||||||
Phosphatidyl-L-serine | 51446-62-9 | sc-507548 | 10 g | $46.00 | ||
Annexin IV has an affinity for phosphatidylserine, and increasing levels of this phospholipid might enhance Annexin IV activity. | ||||||
Adenosine 5′-Triphosphate, disodium salt | 987-65-5 | sc-202040 sc-202040A | 1 g 5 g | $39.00 $75.00 | 9 | |
ATP can influence intracellular calcium signaling, potentially affecting Annexin IV activity. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $55.00 $131.00 $203.00 $317.00 | 23 | |
A compound that increases intracellular calcium levels, potentially enhancing Annexin IV activation. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
An inhibitor of the endoplasmic reticulum Ca2+-ATPase, leading to increased cytosolic calcium levels and potentially enhancing Annexin IV activity. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
As a secondary messenger, cAMP can modulate various signaling pathways, potentially influencing Annexin IV activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Known to increase cAMP levels, Forskolin can indirectly affect pathways that could activate Annexin IV. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $47.00 $136.00 $492.00 $4552.00 | 74 | |
A cAMP analog that can modulate cellular signaling pathways, potentially influencing Annexin IV activity. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Known to disrupt membrane trafficking, Brefeldin A might indirectly influence Annexin IV activity related to membrane processes. | ||||||