Akt Inhibitors
Santa Cruz Biotechnology now offers a broad range of Akt Inhibitors. The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKBβ or RacPK-β) and Akt 3 (also designated PKBγ or thyoma viral proto-oncogene 3). Akt1 and Akt2 are activated by PDGF stimulation. The activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor Wortmannin, suggesting that the protein signals downstream of the PI kinases. Akt Inhibitors offered by Santa Cruz inhibit Akt and, in some cases, other serine/threonine kinases and oncogene related proteins. View detailed Akt Inhibitor specifications, including Akt Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
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SEE ALSO...
- Akt Antibodies for 10 µg trial size samples
- ChemCruz™ Chemical Akt Activators or Akt Substrates for functional analysis of cellular responses to Akt
| PRODUCT NAME/Application | CAS | Catalog # | QUANTITY | Price | Citations | RATING | |
|---|---|---|---|---|---|---|---|
17-AAGA potent Hsp90 inhibitor for tumor cells | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $65.00 $150.00 | 10 |
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Akt Inhibitor IVAn Inhibitor of Akt protein kinase | 681281-88-9 | sc-203809 sc-203809A | 5 mg 25 mg | $170.00 $681.00 | 24 |
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Akt InhibitorA phosphatidylinositol ether analog that potently and selectively inhibits Akt | sc-394003 | 1 mg | $240.00 | 4 |
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SH-6An inhibitor of Akt (PKB) activation without affecting activation of the upstream kinase PDK-1 | sc-205974 sc-205974A | 0.5 mg 1 mg | $466.00 $818.00 | 2 |
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Palomid 529A novel PI3K/Akt/mTOR inhibitor with a GI50 of <35 µM in the NCI-60 cell lines panel | 914913-88-5 | sc-364563 sc-364563A | 10 mg 50 mg | $300.00 $1,000.00 | 0 |
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Akt Inhibitor XA cell permeable, reversible, and selective Akt phosphorylation inhibitor | 925681-41-0 | sc-203811A sc-203811 sc-203811B sc-203811C sc-203811D sc-203811E | 1 mg 5 mg 10 mg 25 mg 50 mg 100 mg | $190.00 $225.00 $430.00 $900.00 $1,503.00 $2,700.00 | 19 |
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GSK 690693An ATP-competitive pan-Akt kinase inhibitor with potential antiproliferative and apoptotic effects | 937174-76-0 | sc-363280 sc-363280A | 10 mg 50 mg | $255.00 $1,071.00 | 2 |
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FisetinA potent sirtuin activating compound (STAC), antiinflammatory and anticancer agent | 528-48-3 | sc-276440 | 50 mg | $50.00 | 2 |
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FPA 124An Akt/PKB inhibitor that Inhibits cell proliferation in various cancer cell lines in vitro | 902779-59-3 | sc-361179 sc-361179A | 10 mg 50 mg | $119.00 $670.00 | 1 |
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SH-5An Inhibitor of Akt activation | sc-205973 sc-205973A | 0.5 mg 1 mg | $148.00 $251.00 | 0 |
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Tetrahydro CurcuminA major metabolite of Curcumin | 36062-04-1 | sc-391609 | 1 g | $200.00 | 0 |
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MiltefosineA PI 3-kinase and Akt inhibitor that also inhibits anti-IgE induced histamine release | 58066-85-6 | sc-203135 | 50 mg | $73.00 | 2 |
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PerifosineAn alkylphospholipid which inhibits Akt activation and the anti-apoptotic MAPK pathway | 157716-52-4 | sc-364571 sc-364571A | 5 mg 10 mg | $180.00 $315.00 | 0 |
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CH5132799A PI3K and FRAP inhibitor | 1007207-67-1 | sc-364460 sc-364460A | 5 mg 50 mg | $360.00 $1,650.00 | 0 |
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AGL 2263A cell-permeable benzoxazolone-containing bioisostere of tyrphostin AG 538; acts as an inhibitor of insulin receptor | sc-221223 | 5 mg | $300.00 | 1 |
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Akt Inhibitor XIA cell-permeable copper complex that inhibits Akt kinase activity | 902779-59-3 | sc-221229 | 5 mg | $80.00 | 3 |
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Akt Inhibitor IX, API-59CJ-OMeSelectively and potently induces apoptosis in cells with elevated Akt activity | 98510-80-6 | sc-203810 | 5 mg | $280.00 | 2 |
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PIK-90A selective inhibitor of PI3K isoforms | 677338-12-4 | sc-364587 sc-364587A | 5 mg 50 mg | $105.00 $555.00 | 0 |
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PIT 1An apoptosis inducing selective PIP3 antagonist | 53501-41-0 | sc-361293 sc-361293A | 10 mg 50 mg | $135.00 $595.00 | 0 |
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TriciribineA tricyclic nucleoside that induces apoptosis and has antineoplastic and antiviral activity | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $100.00 $135.00 | 14 |
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BML-257An AKT1 translocation and HCV NS5B RdRp inhibitor | 32387-96-5 | sc-200666 sc-200666A | 10 mg 50 mg | $72.00 $286.00 | 2 |
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Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2A potent and selective inhibitor of Akt1/2, and mild inhibitor of Akt3 | 612847-09-3 | sc-202048 sc-202048A | 1 mg 5 mg | $190.00 $250.00 | 20 |
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Naltrindole HydrochlorideA δ opioid (DOR) receptor antagonist | 111469-81-9 | sc-202236 | 5 mg | $112.00 | 1 |
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HonokiolA biphenyl neolignan from Magnolia extract that inhibits phosphorylation of Akt, p44/42 MAPK, and src | 35354-74-6 | sc-202653 sc-202653A | 10 mg 25 mg | $118.00 $178.00 | 2 |
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API-1A PKB inhibitor that halts Akt membrane translocation | 36707-00-3 | sc-361106 | 10 mg | $275.00 | 0 |
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EnzastaurinA potent inhibitor of PKCβ, PKCα, PKCγ and PKCε | 170364-57-5 | sc-364488 sc-364488A | 10 mg 50 mg | $135.00 $555.00 | 0 |
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PHT-427A pleckstrin homology domain inhibitor to Akt and PKB Kinase (PDPK1) | 1191951-57-1 | sc-364582 sc-364582A | 10 mg 50 mg | $68.00 $405.00 | 0 |
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DeguelinAn inhibitor of Cox-2 | 522-17-8 | sc-200657 sc-200657A sc-200657B | 5 mg 25 mg 500 mg | $67.00 $268.00 $1,821.00 | 1 |
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Akt Inhibitor XII, Isozyme-Selective, Akti-2A cell-permeable Akt1/2 inhibitor with improved solubility and Ak2 selectivity | sc-221230 | 2 mg | $480.00 | 0 |
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Akt Inhibitor XIII, Isozyme-Selective, Akti2-1/2A cell-permeable and water soluble analog of Akt Inhibitor VIII | sc-221231 | 2 mg | $480.00 | 1 |
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Akt1/2 kinase InhibitorAn Isozyme selective Akt1/2 kinase inhibitor | sc-300173 | 5 mg | $209.00 | 2 |
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AT7867A potent ATP-competitive inhibitor of Akt1, Akt2 and Akt3 | 857531-00-1 | sc-364417 sc-364417A | 10 mg 50 mg | $450.00 $1,300.00 | 0 |
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10-DEBC hydrochlorideA selective inhibitor of Akt/PKB | 201788-90-1 | sc-203459 sc-203459A | 10 mg 50 mg | $129.00 $548.00 | 8 |
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PDK1/Akt/Flt Dual Pathway InhibitorA cell-permeable compound that selectively induces apoptosis | 331253-86-2 | sc-222144 | 5 mg | $236.00 | 0 |
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MK-2206 dihydrochlorideA highly selective pan-Akt inhibitor activated by the pleckstrin homology domain | 1032350-13-2 | sc-364537 sc-364537A | 5 mg 10 mg | $165.00 $309.00 | 25 |
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Akt Inhibitor IIIAn Akt activation inhibtor with little effect on phosphorylation of downstream kinases | sc-221228 | 1 mg | $400.00 | 0 |
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