Akt Inhibitors

Santa Cruz Biotechnology now offers a broad range of Akt Inhibitors. The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKBβ or RacPK-β) and Akt 3 (also designated PKBγ or thyoma viral proto-oncogene 3). Akt1 and Akt2 are activated by PDGF stimulation. The activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor Wortmannin, suggesting that the protein signals downstream of the PI kinases. Akt Inhibitors offered by Santa Cruz inhibit Akt and, in some cases, other serine/threonine kinases and oncogene related proteins. View detailed Akt Inhibitor specifications, including Akt Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/ApplicationCASCatalog #QUANTITYPriceCitationsRATING
17-AAG
A potent Hsp90 inhibitor for tumor cells
75747-14-7sc-200641
sc-200641A
1 mg
5 mg
$65.00
$150.00
10
(2)
Akt Inhibitor IV
An Inhibitor of Akt protein kinase
681281-88-9sc-203809
sc-203809A
5 mg
25 mg
$170.00
$681.00
24
(1)
Akt Inhibitor
A phosphatidylinositol ether analog that potently and selectively inhibits Akt
sc-394003
1 mg
$240.00
4
(1)
SH-6
An inhibitor of Akt (PKB) activation without affecting activation of the upstream kinase PDK-1
sc-205974
sc-205974A
0.5 mg
1 mg
$466.00
$818.00
2
(0)
Palomid 529
A novel PI3K/Akt/mTOR inhibitor with a GI50 of <35 µM in the NCI-60 cell lines panel
914913-88-5sc-364563
sc-364563A
10 mg
50 mg
$300.00
$1,000.00
0
(0)
Akt Inhibitor X
A cell permeable, reversible, and selective Akt phosphorylation inhibitor
925681-41-0sc-203811A
sc-203811
sc-203811B
sc-203811C
sc-203811D
sc-203811E
1 mg
5 mg
10 mg
25 mg
50 mg
100 mg
$190.00
$225.00
$430.00
$900.00
$1,503.00
$2,700.00
19
(1)
GSK 690693
An ATP-competitive pan-Akt kinase inhibitor with potential antiproliferative and apoptotic effects
937174-76-0sc-363280
sc-363280A
10 mg
50 mg
$255.00
$1,071.00
2
(1)
Fisetin
A potent sirtuin activating compound (STAC), antiinflammatory and anticancer agent
528-48-3sc-276440
50 mg
$50.00
2
(1)
FPA 124
An Akt/PKB inhibitor that Inhibits cell proliferation in various cancer cell lines in vitro
902779-59-3sc-361179
sc-361179A
10 mg
50 mg
$119.00
$670.00
1
(0)
SH-5
An Inhibitor of Akt activation
sc-205973
sc-205973A
0.5 mg
1 mg
$148.00
$251.00
0
(1)
Tetrahydro Curcumin
A major metabolite of Curcumin
36062-04-1sc-391609
1 g
$200.00
0
(0)
Miltefosine
A PI 3-kinase and Akt inhibitor that also inhibits anti-IgE induced histamine release
58066-85-6sc-203135
50 mg
$73.00
2
(1)
Perifosine
An alkylphospholipid which inhibits Akt activation and the anti-apoptotic MAPK pathway
157716-52-4sc-364571
sc-364571A
5 mg
10 mg
$180.00
$315.00
0
(2)
CH5132799
A PI3K and FRAP inhibitor
1007207-67-1sc-364460
sc-364460A
5 mg
50 mg
$360.00
$1,650.00
0
(0)
AGL 2263
A cell-permeable benzoxazolone-containing bioisostere of tyrphostin AG 538; acts as an inhibitor of insulin receptor
sc-221223
5 mg
$300.00
1
(1)
Akt Inhibitor XI
A cell-permeable copper complex that inhibits Akt kinase activity
902779-59-3sc-221229
5 mg
$80.00
3
(1)
Akt Inhibitor IX, API-59CJ-OMe
Selectively and potently induces apoptosis in cells with elevated Akt activity
98510-80-6sc-203810
5 mg
$280.00
2
(1)
PIK-90
A selective inhibitor of PI3K isoforms
677338-12-4sc-364587
sc-364587A
5 mg
50 mg
$105.00
$555.00
0
(0)
PIT 1
An apoptosis inducing selective PIP3 antagonist
53501-41-0sc-361293
sc-361293A
10 mg
50 mg
$135.00
$595.00
0
(0)
Triciribine
A tricyclic nucleoside that induces apoptosis and has antineoplastic and antiviral activity
35943-35-2sc-200661
sc-200661A
1 mg
5 mg
$100.00
$135.00
14
(1)
BML-257
An AKT1 translocation and HCV NS5B RdRp inhibitor
32387-96-5sc-200666
sc-200666A
10 mg
50 mg
$72.00
$286.00
2
(0)
Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2
A potent and selective inhibitor of Akt1/2, and mild inhibitor of Akt3
612847-09-3sc-202048
sc-202048A
1 mg
5 mg
$190.00
$250.00
20
(1)
Naltrindole Hydrochloride
A δ opioid (DOR) receptor antagonist
111469-81-9sc-202236
5 mg
$112.00
1
(1)
Honokiol
A biphenyl neolignan from Magnolia extract that inhibits phosphorylation of Akt, p44/42 MAPK, and src
35354-74-6sc-202653
sc-202653A
10 mg
25 mg
$118.00
$178.00
2
(1)
API-1
A PKB inhibitor that halts Akt membrane translocation
36707-00-3sc-361106
10 mg
$275.00
0
(0)
Enzastaurin
A potent inhibitor of PKCβ, PKCα, PKCγ and PKCε
170364-57-5sc-364488
sc-364488A
sc-364488B
10 mg
50 mg
200 mg
$135.00
$555.00
$1,365.00
0
(1)
PHT-427
A pleckstrin homology domain inhibitor to Akt and PKB Kinase (PDPK1)
1191951-57-1sc-364582
sc-364582A
10 mg
50 mg
$68.00
$405.00
0
(0)
Deguelin
An inhibitor of Cox-2
522-17-8sc-200657
sc-200657A
sc-200657B
5 mg
25 mg
500 mg
$67.00
$268.00
$1,821.00
1
(1)
Akt Inhibitor XII, Isozyme-Selective, Akti-2
A cell-permeable Akt1/2 inhibitor with improved solubility and Ak2 selectivity
sc-221230
2 mg
$480.00
0
(0)
Akt Inhibitor XIII, Isozyme-Selective, Akti2-1/2
A cell-permeable and water soluble analog of Akt Inhibitor VIII
sc-221231
2 mg
$480.00
1
(0)
Akt1/2 kinase Inhibitor
An Isozyme selective Akt1/2 kinase inhibitor
sc-300173
5 mg
$209.00
3
(1)
AT7867
A potent ATP-competitive inhibitor of Akt1, Akt2 and Akt3
857531-00-1sc-364417
sc-364417A
10 mg
50 mg
$450.00
$1,300.00
0
(0)
10-DEBC hydrochloride
A selective inhibitor of Akt/PKB
201788-90-1sc-203459
sc-203459A
10 mg
50 mg
$129.00
$548.00
8
(1)
PDK1/Akt/Flt Dual Pathway Inhibitor
A cell-permeable compound that selectively induces apoptosis
331253-86-2sc-222144
5 mg
$236.00
0
(0)
MK-2206 dihydrochloride
A highly selective pan-Akt inhibitor activated by the pleckstrin homology domain
1032350-13-2sc-364537
sc-364537A
5 mg
10 mg
$165.00
$309.00
29
(1)
Akt Inhibitor III
An Akt activation inhibtor with little effect on phosphorylation of downstream kinases
sc-221228
1 mg
$400.00
0
(0)

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