Akt Inhibitor MF: C30H58O10
MW: 578.78
A phosphatidylinositol ether analog that potently and selectively inhibits Akt.

Akt Inhibitor

Akt Inhibitor is rated 5.0 out of 5 by 1.
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Alternate Names: 1L6-Hydroxymethyl-chiro-inositol-2-(R)-2-O-methyl-3-O-octadecyl-sn-glycerocarbonate
Application: Akt Inhibitor is a phosphatidylinositol ether analog that potently and selectively inhibits Akt
Purity: ≥98%
Molecular Weight: 578.78
Molecular Formula: C30H58O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Akt Inhibitor is a phosphatidylinositol ether analog that potently and selectively inhibits Akt (PKB) (IC50 of 5.0 μM). It moderately inhibits PI 3-kinase activity (IC50 = 83.0 μM). Akt Inhibitor also inhibits the growth of various cancer cell lines with IC50 values in the 1 - 10 μM range.

Physical State :
Solid
Solubility :
Soluble in DMSO.
Storage :
Store at -20° C
Density :
~1.13 g/cm3 (Predicted)
Refractive Index :
n20D ~1.51 (Predicted)
IC50 :
Akt: IC50 = 5.0 µM; PI 3-K activity : IC50 = 83.0 µM; growth of various cancer cell lines: IC50 = 1-10 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
16760281
SMILES :
CCCCCCCCCCCCCCCCCCOC[[email protected]](COC(=O)OC1C(C(C(C(C1O)O)O)CO)O)OC

Download SDS (MSDS)

Certificate of Analysis

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Akt Inhibitor  Product Citations

See how others have used Akt Inhibitor. Click on the entry to view the PubMed entry .

Citations 1 to 5 of 5 total

PMID: # 26634216  Hidalgo, MA. et al. 2015. J Immunol Res. 2015: 120348.

PMID: # 25198901  Yang, WH. et al. 2014. Int J Mol Sci. 15: 15778-90.

PMID: # 25229320  Liu, C. et al. 2014. FEBS J. 281: 5159-71.

PMID: # 23278864  Lu, J. et al. 2013. J Anim Physiol Anim Nutr (Berl). 97: 1170-8.

PMID: # 22139302  Mol Cell Biochem. 135-45.

Citations 1 to 5 of 5 total
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Rated 5 out of 5 by from Akt Inhibitor was reported in many articles Akt Inhibitor was reported in many articles as an inhibitor of AKT and the growth of assorted cancer cell lines. -SCBT Publication Review
Date published: 2015-02-02
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